About   Help   FAQ
hml Gene Detail
Summary
  • Symbol
    hml
  • Name
    Hypoplasia of the membranous labyrinth
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:1933750
  • Alliance
    gene page
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 10, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    23 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
homozygotes display a failure to thrive phenotype, do not breed, can not orient in water, are severely hearing impaired or deaf, and have hypoplasia of the membranous labyrinth with a rudimentary tectorial membrane and enlarged scala vestibuli.
References
more
  • Summaries
    All 1
    Phenotypes 1
  • Earliest
    J:175136 Zheng QY, et al., Fine Mapping of a Deafness Mutation hml on Mouse Chromosome 10. Acad J Xian Jiaotong Univ. 2004 Jun;25(3):209-212
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory