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hml Gene Detail
Summary
  • Symbol
    hml
  • Name
    Hypoplasia of the membranous labyrinth
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:1933750
  • Alliance
    gene page
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 10, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    23 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
homozygotes display a failure to thrive phenotype, do not breed, can not orient in water, are severely hearing impaired or deaf, and have hypoplasia of the membranous labyrinth with a rudimentary tectorial membrane and enlarged scala vestibuli.
References
more
  • Summaries
    All 1
    Phenotypes 1
  • Earliest
    J:175136 Zheng QY, et al., Fine Mapping of a Deafness Mutation hml on Mouse Chromosome 10. Acad J Xian Jiaotong Univ. 2004 Jun;25(3):209-212
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory