Hspe1-rs1 MGI Mouse Gene Detail - MGI:1935159 - heat shock protein 1 (chaperonin 10), related sequence 1

Hspe1-rs1 Gene Detail

Symbol

Hspe1-rs1
Name

heat shock protein 1 (chaperonin 10), related sequence 1
Synonyms

10kDa, Cpn10-rs1, EG628438, EPF

Feature Type

protein coding gene

BioType Conflict
IDs

MGI:1935159
NCBI Gene: 628438
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr18:47245206-47245720 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 18, 25.00 cM, cytoband C
Mapping Data

2 experiments

SNPs within 2kb

102 from dbSNP Build 142
Strain Annotations

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1935159	protein coding gene	Chr18:47245206-47245741 (+)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Human Ortholog

HSPE1, heat shock protein family E (Hsp10) member 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

HSPE1, heat shock protein family E (Hsp10) member 1
Synonyms

CPN10, EPF, GROES, HSP10
Links

HGNC:5269

NCBI Gene ID: 3336

neXtProt AC: NX_P61604

UniProt: P61604
Chr Location

2q33.1; chr2:197500140-197503449 (+) GRCh38

MGI Vertebrate Homology

Hspe1-rs1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: HSPE1
Gene Tree

Hspe1-rs1

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Phenotype Summary

1 phenotype reference

All Mutations and Alleles

1
Spontaneous

1
Genomic Mutations

1 involving Hspe1-rs1
Find Mice (IMSR)

1 strains or lines available

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All GO Annotations

12
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

1

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

8
RefSeq

1
UniProt

1

Ensembl

ENSMUSG00000117621 (Evidence)
NCBI Gene

628438

			Length	Strain/Species	Flank
genomic	ENSMUSG00000117621	Ensembl Gene Model \| MGI Sequence Detail	515	C57BL/6J	± kb
transcript	ENSMUST00000234633	Ensembl \| MGI Sequence Detail	515	Not Applicable
polypeptide	ENSMUSP00000157281	Ensembl \| MGI Sequence Detail	102	Not Applicable

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UniProt

1 Sequence
InterPro Domains

IPR020818 GroES chaperonin family

IPR037124 GroES chaperonin superfamily

IPR011032 GroES-like superfamily

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All nucleic 1

cDNA 1

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MGI:3644923

Summaries

All 15

Gene Ontology 5

Phenotypes 1
Earliest

J:69088 Fletcher BH, et al., The murine chaperonin 10 gene family contains an intronless, putative gene for early pregnancy factor, Cpn10-rs1. Mamm Genome. 2001 Feb;12(2):133-40
Latest

J:327181 Lewis MA, et al., Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme. BMC Biol. 2022 Mar 17;20(1):67

TSS for Hspe1-rs1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr150972	Chr18:47245204-47245216 (+)	4 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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