Dqx1 MGI Mouse Gene Detail - MGI:2136388 - DEAQ RNA-dependent ATPase

Symbol

Dqx1
Name

DEAQ RNA-dependent ATPase
Synonyms

2310066E11Rik

Feature Type

protein coding gene
IDs

MGI:2136388
NCBI Gene: 93838
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr6:83034825-83044299 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 6, 35.94 cM, cytoband D1
Mapping Data

3 experiments

SNPs within 2kb

260 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2136388	protein coding gene	Chr6:83034728-83044299 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0030913	protein coding gene	Chr6:84061619-84070740 (+)
A/J	MGP_AJ_G0030882	protein coding gene	Chr6:80848282-80856967 (+)
AKR/J	MGP_AKRJ_G0030810	protein coding gene	Chr6:83177648-83187141 (+)
BALB/cJ	MGP_BALBcJ_G0030892	protein coding gene	Chr6:80861148-80870918 (+)
C3H/HeJ	MGP_C3HHeJ_G0030818	protein coding gene	Chr6:101194909-101206008 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0031352	protein coding gene	Chr6:86340894-86350359 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0028538	protein coding gene	Chr6:79206965-79215732 (+)
CAST/EiJ	MGP_CASTEiJ_G0030001	protein coding gene	Chr6:83177732-83187547 (+)
CBA/J	MGP_CBAJ_G0030579	protein coding gene	Chr6:89753167-89762651 (+)
DBA/2J	MGP_DBA2J_G0030732	protein coding gene	Chr6:80167802-80178015 (+)
FVB/NJ	MGP_FVBNJ_G0030685	protein coding gene	Chr6:79375519-79384820 (+)
LP/J	MGP_LPJ_G0030811	protein coding gene	Chr6:84055427-84064910 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0030721	protein coding gene	Chr6:94058012-94067153 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0031376	protein coding gene	Chr6:82990400-83001086 (+)
PWK/PhJ	MGP_PWKPhJ_G0029716	protein coding gene	Chr6:79060092-79069677 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0029544	protein coding gene	Chr6:81836989-81846365 (+)
WSB/EiJ	MGP_WSBEiJ_G0030082	protein coding gene	Chr6:83430071-83438742 (+)

Human Ortholog

DQX1, DEAQ-box RNA dependent ATPase 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

DQX1, DEAQ-box RNA dependent ATPase 1
Links

HGNC:20410

NCBI Gene ID: 165545

neXtProt AC: NX_Q8TE96

UniProt: Q8TE96
Chr Location

2p13.1; chr2:74518131-74526281 (-) GRCh38

MGI Vertebrate Homology

Dqx1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: DQX1
Gene Tree

Dqx1

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Phenotype Summary

8 phenotype references

All Mutations and Alleles

4
Endonuclease-mediated

2
Spontaneous

1
Targeted

1
Genomic Mutations

2 involving Dqx1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

39 strains or lines available

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All GO Annotations

18
GO References

7

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

710
Tissues

1
cDNA Data

4
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase dqx1

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All Sequences

46
RefSeq

15
UniProt

2
CCDS

CCDS20268.1

Ensembl

ENSMUSG00000009145 (Evidence)
NCBI Gene

93838

			Length	Strain/Species	Flank
genomic	ENSMUSG00000009145	Ensembl Gene Model \| MGI Sequence Detail	9475	C57BL/6J	± kb
transcript	ENSMUST00000077502	Ensembl \| MGI Sequence Detail	3257	Not Applicable
polypeptide	ENSMUSP00000076708	Ensembl \| MGI Sequence Detail	718	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000006684 ATP-dependent RNA helicase DQX1

(term hierarchy)
EC

3.6.4.12
InterPro Domains

IPR011709 DEAD-box helicase, OB fold

IPR007502 Helicase-associated domain

IPR048333 Helicase associated domain (HA2), winged-helix domain

IPR014001 Helicase superfamily 1/2, ATP-binding domain

IPR027417 P-loop containing nucleoside triphosphate hydrolase

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All nucleic 6

cDNA 6

Microarray probesets 3

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MGI:1916939

Summaries

All 32

Developmental Gene Expression 1

Gene Ontology 7

Phenotypes 8
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:330636 Iwata S, et al., An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain. G3 (Bethesda). 2021;11(8)

TSS for Dqx1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr57283	Chr6:83033541-83033559 (+)	-1,275 bp
Tssr57284	Chr6:83033749-83033765 (+)	-1,068 bp
Tssr57285	Chr6:83033991-83034013 (+)	-823 bp
Tssr57286	Chr6:83034034-83034049 (+)	-783 bp
Tssr57287	Chr6:83034247-83034281 (+)	-561 bp
Tssr57288	Chr6:83035049-83035085 (+)	242 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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