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Fzd10 Gene Detail
Summary
  • Symbol
    Fzd10
  • Name
    frizzled class receptor 10
  • Synonyms
    Fz-10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136761
    NCBI Gene: 93897
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:128678170-128681157 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 67.67 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    127 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136761
 protein coding gene Chr5:128677908-128681157 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030119
 protein coding gene Chr5:132628841-132632086 (+)
A/J MGP_AJ_G0030086
 protein coding gene Chr5:127055061-127058308 (+)
AKR/J MGP_AKRJ_G0030020
 protein coding gene Chr5:131187498-131190747 (+)
BALB/cJ MGP_BALBcJ_G0030096
 protein coding gene Chr5:128402655-128405902 (+)
C3H/HeJ MGP_C3HHeJ_G0029813
 protein coding gene Chr5:131753638-131756794 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030549
 protein coding gene Chr5:137705851-137709088 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027774
 protein coding gene Chr5:121479638-121482865 (+)
CAST/EiJ MGP_CASTEiJ_G0029222
 protein coding gene Chr5:131000118-131003355 (+)
CBA/J MGP_CBAJ_G0029783
 protein coding gene Chr5:143086067-143089314 (+)
DBA/2J MGP_DBA2J_G0029933
 protein coding gene Chr5:127046078-127049328 (+)
FVB/NJ MGP_FVBNJ_G0029889
 protein coding gene Chr5:126098349-126101595 (+)
LP/J MGP_LPJ_G0030022
 protein coding gene Chr5:133142126-133145371 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029920
 protein coding gene Chr5:146483214-146486461 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030590
 protein coding gene Chr5:130844795-130848040 (+)
PWK/PhJ MGP_PWKPhJ_G0028936
 protein coding gene Chr5:125934758-125937934 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028773
 protein coding gene Chr5:128416828-128420065 (+)
WSB/EiJ MGP_WSBEiJ_G0029296
 protein coding gene Chr5:131507955-131511201 (+)



Homology
more
  • Human Ortholog
    FZD10, frizzled class receptor 10
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FZD10, frizzled class receptor 10
  • Synonyms
    CD350, Fz10, FZ-10, FzE7, hFz10
  • Links
    NCBI Gene ID: 11211
    neXtProt AC: NX_Q9ULW2
    UniProt: Q9ULW2

  • Chr Location
    12q24.33; chr12:130162459-130165740 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Homozygous mutation of this gene does not appear to result in a phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1225
  • Tissues
    348
  • cDNA Data
    18
  • Literature Summary
    56
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 93897 NCBI Gene Model | MGI Sequence Detail 2988 C57BL/6J ±  kb
transcript NM_175284 RefSeq | MGI Sequence Detail 3005 CD-1  
polypeptide Q8BKG4 UniProt | EBI | MGI Sequence Detail 582 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    cDNA 18
    Primer pair 12
    Other 4

    Microarray probesets 3
References
more
  • Summaries
    All 88
    Developmental Gene Expression 56
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:334527 Weiss AC, et al., Permissive ureter specification by TBX18-mediated repression of metanephric gene expression. Development. 2023 Mar 15;150(6):dev201048
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory