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Slc28a3 Gene Detail
Summary
  • Symbol
    Slc28a3
  • Name
    solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
  • Synonyms
    Cnt3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137361
    NCBI Gene: 114304
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:58701121-58758691 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 31.07 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1862 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137361
 protein coding gene Chr13:58693213-58758691 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020635
 protein coding gene Chr13:58194644-58265023 (-)
A/J MGP_AJ_G0020589
 protein coding gene Chr13:56031147-56098832 (-)
AKR/J MGP_AKRJ_G0020567
 protein coding gene Chr13:57700756-57768235 (-)
BALB/cJ MGP_BALBcJ_G0020585
 protein coding gene Chr13:56289174-56354245 (-)
C3H/HeJ MGP_C3HHeJ_G0020384
 protein coding gene Chr13:57503097-57570312 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021019
 protein coding gene Chr13:59976263-60042580 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018601
 protein coding gene Chr13:53924233-53987934 (-)
CAST/EiJ MGP_CASTEiJ_G0019898
 protein coding gene Chr13:57640748-57707445 (-)
CBA/J MGP_CBAJ_G0020344
 protein coding gene Chr13:62233529-62304700 (-)
DBA/2J MGP_DBA2J_G0020467
 protein coding gene Chr13:55578035-55643065 (-)
FVB/NJ MGP_FVBNJ_G0020446
 protein coding gene Chr13:55060754-55124094 (-)
LP/J MGP_LPJ_G0020543
 protein coding gene Chr13:58460038-58529308 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020475
 protein coding gene Chr13:61586391-61663427 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021062
 protein coding gene Chr13:57301500-57373652 (-)
PWK/PhJ MGP_PWKPhJ_G0019654
 protein coding gene Chr13:55590853-55656219 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019481
 protein coding gene Chr13:56203752-56270864 (-)
WSB/EiJ MGP_WSBEiJ_G0019960
 protein coding gene Chr13:57735224-57803520 (-)



Homology
more
  • Human Ortholog
    SLC28A3, solute carrier family 28 member 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC28A3, solute carrier family 28 member 3
  • Synonyms
    CNT3
  • Links
    NCBI Gene ID: 64078
    neXtProt AC: NX_Q9HAS3
    UniProt: Q9HAS3

  • Chr Location
    9q21.32-q21.33; chr9:84275457-84368727 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    810
  • Tissues
    95
  • cDNA Data
    80
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 114304 NCBI Gene Model | MGI Sequence Detail 57571 C57BL/6J ±  kb
    transcript NM_022317 RefSeq | MGI Sequence Detail 4565 C57BL/6  
    polypeptide Q9ERH8 UniProt | EBI | MGI Sequence Detail 703 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000015053 solute carrier family 28 member 3
      (term hierarchy)
    • InterPro Domains
      IPR008276 Concentrative nucleoside transporter
      IPR011657 Concentrative nucleoside transporter C-terminal domain
      IPR018270 Concentrative nucleoside transporter, metazoan/bacterial
      IPR002668 Concentrative nucleoside transporter N-terminal domain
      IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain
    Molecular
    Reagents
    less
    • All nucleic 82
      cDNA 81
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 2
      Gene Ontology 7
      Phenotypes 11
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory