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Ugt1a6a Gene Detail
Summary
  • Symbol
    Ugt1a6a
  • Name
    UDP glucuronosyltransferase 1 family, polypeptide A6A
  • Synonyms
    UGT1.6, Ugt1a6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137698
    NCBI Gene: 94284
  • Member of
    Ugt1 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:88062531-88146719 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 44.52 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2204 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137698
 protein coding gene Chr1:88062531-88147724 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016276
 protein coding gene Chr1:89491879-89628377 (+)
A/J MGP_AJ_G0016259
 protein coding gene Chr1:86198505-86334105 (+)
AKR/J MGP_AKRJ_G0016220
 protein coding gene Chr1:88761301-88898479 (+)
BALB/cJ MGP_BALBcJ_G0016216
 protein coding gene Chr1:86366636-86472410 (+)
C3H/HeJ MGP_C3HHeJ_G0016044
 protein coding gene Chr1:89026333-89122337 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016674
 protein coding gene Chr1:92846034-92996654 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014389
 protein coding gene Chr1:80583529-80707867 (+)
CAST/EiJ MGP_CASTEiJ_G0015630
 protein coding gene Chr1:88223435-88339172 (+)
CBA/J MGP_CBAJ_G0016020
 protein coding gene Chr1:95835203-95995691 (+)
DBA/2J MGP_DBA2J_G0016123
 protein coding gene Chr1:85445307-85575533 (+)
FVB/NJ MGP_FVBNJ_G0016122
 protein coding gene Chr1:84577446-84658645 (+)
LP/J MGP_LPJ_G0016193
 protein coding gene Chr1:90567900-90703609 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016147
 protein coding gene Chr1:99125819-99344396 (+)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0015194
 protein coding gene Chr1:87776503-87876017 (+)
WSB/EiJ MGP_WSBEiJ_G0015689
 protein coding gene Chr1:88531228-88627325 (+)



Homology
more
  • Human Ortholog
    UGT1A6, UDP glucuronosyltransferase family 1 member A6
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UGT1A6, UDP glucuronosyltransferase family 1 member A6
  • Synonyms
    GNT1, HLUGP, HLUGP1, hUG-BR1, UDPGT, UDPGT 1-6, UGT1, UGT1-01, UGT1-03, UGT1-05, UGT1-06, UGT1.1, UGT1.3, UGT1.5, UGT1.6, UGT-1A, UGT1A, UGT1A1, UGT1A3, UGT1A5, UGT1A6S, UGT-1C, UGT1C, UGT-1E, UGT1E, UGT-1F, UGT1F
  • Links
    NCBI Gene ID: 54578
    neXtProt AC: NX_P19224
    UniProt: P19224

  • Chr Location
    2q37.1; chr2:233691607-233773300 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human UGT1A6 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    954
  • Tissues
    100
  • cDNA Data
    6
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054545 Ensembl Gene Model | MGI Sequence Detail 84189 C57BL/6J ±  kb
transcript ENSMUST00000113134 Ensembl | MGI Sequence Detail 2297 Not Applicable  
polypeptide ENSMUSP00000108759 Ensembl | MGI Sequence Detail 531 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 9
    Genomic 1
    cDNA 8

    Microarray probesets 1
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 4
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory