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Cercam Gene Detail
Summary
  • Symbol
    Cercam
  • Name
    cerebral endothelial cell adhesion molecule
  • Synonyms
    Ceecam1, CerCAM
  • Feature Type
    protein coding gene
  • IDs
    MGI:2139134
    NCBI Gene: 99151
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:29759176-29772852 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 20.76 cM, cytoband B
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    312 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2139134
protein coding gene Chr2:29735442-29772857 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025546
protein coding gene Chr2:28040567-28053948 (+)
A/J MGP_AJ_G0025524
protein coding gene Chr2:26941476-26954961 (+)
AKR/J MGP_AKRJ_G0025493
protein coding gene Chr2:27853274-27869461 (+)
BALB/cJ MGP_BALBcJ_G0025519
protein coding gene Chr2:27073986-27088046 (+)
C3H/HeJ MGP_C3HHeJ_G0025281
protein coding gene Chr2:27778314-27796071 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025964
protein coding gene Chr2:28949467-28967339 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023373
protein coding gene Chr2:25731327-25745237 (+)
CAST/EiJ MGP_CASTEiJ_G0024744
protein coding gene Chr2:27668056-27684405 (+)
CBA/J MGP_CBAJ_G0025258
protein coding gene Chr2:29954390-29976763 (+)
DBA/2J MGP_DBA2J_G0025391
protein coding gene Chr2:26738104-26751793 (+)
FVB/NJ MGP_FVBNJ_G0025354
protein coding gene Chr2:26540743-26555910 (+)
LP/J MGP_LPJ_G0025477
protein coding gene Chr2:27959094-27976990 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025384
protein coding gene Chr2:29878618-29894295 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026023
protein coding gene Chr2:27773938-27789663 (+)
PWK/PhJ MGP_PWKPhJ_G0024490
protein coding gene Chr2:26555284-26581136 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024290
protein coding gene Chr2:27851957-27866865 (+)
WSB/EiJ MGP_WSBEiJ_G0024812
protein coding gene Chr2:27889436-27905481 (+)



Homology
more
  • Human Ortholog
    CERCAM, cerebral endothelial cell adhesion molecule
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CERCAM, cerebral endothelial cell adhesion molecule
  • Synonyms
    CEECAM1, GLT25D3
  • Links
    NCBI Gene ID: 51148
    neXtProt AC: NX_Q5T4B2
    UniProt: Q5T4B2

  • Chr Location
    9q34.11; chr9:128411751-128437351 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039787 Ensembl Gene Model | MGI Sequence Detail 13677 C57BL/6J ±  kb
transcript ENSMUST00000047521 Ensembl | MGI Sequence Detail 2715 Not Applicable  
polypeptide ENSMUSP00000041622 Ensembl | MGI Sequence Detail 592 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000005362 glycosyltransferase 25 family member 3
  • InterPro Domains
    IPR050757 Collagen-modifying Glycosyltransferase 25
    IPR002654 Glycosyl transferase, family 25
    IPR029044 Nucleotide-diphospho-sugar transferases
  • GlyGen
    A3KGW5 4 sites, 1 N-linked glycan (2 sites)
Molecular
Reagents
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  • All nucleic 29
    cDNA 29

    Microarray probesets 2
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:83282 Moulson CL, et al., Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5274-9
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory