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Nol6 Gene Detail
Summary
  • Symbol
    Nol6
  • Name
    nucleolar protein family 6 (RNA-associated)
  • Synonyms
    Nrap
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140151
    NCBI Gene: 230082
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:41114427-41124450 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 20.98 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    315 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140151
 protein coding gene Chr4:41114427-41124455 (-)
129S1/SvImJ ENSMUSG00200005277
 protein coding gene Chr4:37956338-37966372 (-)
A/J ENSMUSG00195002764
 protein coding gene Chr4:38332193-38342226 (-)
AKR/J ENSMUSG00220033549
 protein coding gene Chr4:38160261-38170280 (-)
BALB/cJ ENSMUSG00180021415
 protein coding gene Chr4:37918988-37929023 (-)
C3H/HeJ ENSMUSG00175021205
 protein coding gene Chr4:38297643-38307681 (-)
C57BL/6NJ ENSMUSG00215019069
 protein coding gene Chr4:37935229-37945259 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025907
 protein coding gene Chr4:35210105-35220225 (-)
CAST/EiJ ENSTCUG00005004587
 protein coding gene Chr4:37780452-37790500 (-)
CBA/J ENSMUSG00210007285
 protein coding gene Chr4:37998563-38008595 (-)
DBA/2J ENSMUSG00185006431
 protein coding gene Chr4:38072333-38082363 (-)
FVB/NJ ENSMUSG00205014485
 protein coding gene Chr4:37623097-37633158 (-)
JF1/MsJ ENSUMUG00000010063
 protein coding gene Chr4:38014706-38024733 (-)
LP/J ENSMUSG00230037766
 protein coding gene Chr4:41449910-41459943 (-)
NOD/ShiLtJ ENSMUSG00190005920
 protein coding gene Chr4:38021524-38031543 (-)
NZO/HlLtJ ENSMUSG00225006232
 protein coding gene Chr4:45330522-45340541 (-)
PWK/PhJ ENSLUMG00010005874
 protein coding gene Chr4:37572103-37582136 (-)
SPRET/EiJ ENSMSPG00010022897
 protein coding gene Chr4:38510867-38521848 (-)
WSB/EiJ ENSIUOG00005047678
 protein coding gene Chr4:37875189-37885200 (-)



Homology
more
  • Human Ortholog
    NOL6, nucleolar protein 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NOL6, nucleolar protein 6
  • Synonyms
    bA311H10.1, NRAP, UTP22
  • Links
    NCBI Gene ID: 65083
    UniProt: Q9H6R4

  • Chr Location
    9p13.3; chr9:33461353-33473930 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    627
  • Tissues
    21
  • cDNA Data
    106
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 230082 NCBI Gene Model | MGI Sequence Detail 10024 C57BL/6J ±  kb
transcript NM_139236 RefSeq | MGI Sequence Detail 4420 C57BL/6  
polypeptide Q8R5K4 UniProt | EBI | MGI Sequence Detail 1152 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 106
    cDNA 106
    Antibodies 1

    Microarray probesets 4
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:76634 Utama B, et al., Isolation and characterization of a new nucleolar protein, Nrap, that is conserved from yeast to humans. Genes Cells. 2002 Feb;7(2):115-32
  • Latest
    J:380828 Al Adhami H, et al., Systematic identification of factors involved in the silencing of germline genes in mouse embryonic stem cells. Nucleic Acids Res. 2023 Apr 24;51(7):3130-3149
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory