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Mob3c Gene Detail
Summary
  • Symbol
    Mob3c
  • Name
    MOB kinase activator 3C
  • Synonyms
    D130076I06Rik, MOB3C, Mobkl2c
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140623
    NCBI Gene: 100465
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:115685289-115693382 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 53.06 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    281 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140623
 protein coding gene Chr4:115675962-115693382 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028609
 protein coding gene Chr4:116670790-116678887 (+)
A/J MGP_AJ_G0028570
 protein coding gene Chr4:112218257-112226328 (+)
AKR/J MGP_AKRJ_G0028519
 protein coding gene Chr4:114624498-114632587 (+)
BALB/cJ MGP_BALBcJ_G0028591
 protein coding gene Chr4:112845812-112853902 (+)
C3H/HeJ MGP_C3HHeJ_G0028305
 protein coding gene Chr4:116202749-116210839 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029032
 protein coding gene Chr4:121195797-121203890 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026316
 protein coding gene Chr4:106264524-106272978 (+)
CAST/EiJ MGP_CASTEiJ_G0027739
 protein coding gene Chr4:113405158-113413246 (+)
CBA/J MGP_CBAJ_G0028272
 protein coding gene Chr4:124487562-124495650 (+)
DBA/2J MGP_DBA2J_G0028420
 protein coding gene Chr4:112867544-112875615 (+)
FVB/NJ MGP_FVBNJ_G0028388
 protein coding gene Chr4:111352683-111360745 (+)
LP/J MGP_LPJ_G0028522
 protein coding gene Chr4:116889574-116897671 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028415
 protein coding gene Chr4:129505901-129515283 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029069
 protein coding gene Chr4:115782004-115790101 (+)
PWK/PhJ MGP_PWKPhJ_G0027465
 protein coding gene Chr4:109626467-109634728 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027288
 protein coding gene Chr4:112024029-112032147 (+)
WSB/EiJ MGP_WSBEiJ_G0027818
 protein coding gene Chr4:115644542-115652626 (+)



Homology
more
  • Human Ortholog
    MOB3C, MOB kinase activator 3C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MOB3C, MOB kinase activator 3C
  • Synonyms
    MOB1E, MOBKL2C
  • Links
    NCBI Gene ID: 148932
    neXtProt AC: NX_Q70IA8
    UniProt: Q70IA8

  • Chr Location
    1p33; chr1:46607719-46616811 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Gene trapped
    3
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    4 involving Mob3c
  • Find Mice (IMSR)
    16 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    25
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028709 Ensembl Gene Model | MGI Sequence Detail 8094 C57BL/6J ±  kb
transcript ENSMUST00000030477 Ensembl | MGI Sequence Detail 2884 Not Applicable  
polypeptide ENSMUSP00000030477 Ensembl | MGI Sequence Detail 216 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    Genomic 2
    cDNA 25

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory