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Ccz1 Gene Detail
Summary
  • Symbol
    Ccz1
  • Name
    CCZ1 vacuolar protein trafficking and biogenesis associated
  • Feature Type
    protein coding gene
  • IDs
    MGI:2141070
    NCBI Gene: 231874
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:143924727-143951695 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 82.85 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    985 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2141070
 protein coding gene Chr5:143924727-143951744 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030343
 protein coding gene Chr5:149295418-149325890 (-)
A/J no annotation
AKR/J MGP_AKRJ_G0030244
 protein coding gene Chr5:147343125-147372547 (-)
BALB/cJ MGP_BALBcJ_G0030329
 protein coding gene Chr5:144126055-144153235 (-)
C3H/HeJ MGP_C3HHeJ_G0030040
 protein coding gene Chr5:148186932-148214790 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030774
 protein coding gene Chr5:154758438-154787624 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027992
 protein coding gene Chr5:136641288-136707343 (-)
CAST/EiJ MGP_CASTEiJ_G0029445
 protein coding gene Chr5:147697725-147729899 (-)
CBA/J MGP_CBAJ_G0030010
 protein coding gene Chr5:161115350-161145469 (-)
DBA/2J MGP_DBA2J_G0030160
 protein coding gene Chr5:142643910-142673109 (-)
FVB/NJ MGP_FVBNJ_G0030115
 protein coding gene Chr5:141851689-141880331 (-)
LP/J MGP_LPJ_G0030246
 protein coding gene Chr5:149903079-149934888 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030146
 protein coding gene Chr5:163494880-163523672 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030814
 protein coding gene Chr5:147229053-147257011 (-)
PWK/PhJ MGP_PWKPhJ_G0029160
 protein coding gene Chr5:141747690-141774265 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028996
 protein coding gene Chr5:144970420-144997792 (-)
WSB/EiJ MGP_WSBEiJ_G0029518
 protein coding gene Chr5:148034090-148064983 (-)



Homology
more
  • Human Ortholog
    CCZ1, CCZ1 homolog, vacuolar protein trafficking and biogenesis associated
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCZ1, CCZ1 homolog, vacuolar protein trafficking and biogenesis associated
  • Synonyms
    C7orf28A, CCZ1A, CGI-43, H_DJ1163J12.2
  • Links
    NCBI Gene ID: 51622
    neXtProt AC: NX_P86790, NX_P86791
    UniProt: P86791

  • Chr Location
    7p22.1; chr7:5898725-5926550 (+)  GRCh38
  • Human Ortholog
    CCZ1B, CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated
  • Synonyms
    C7orf28A, C7orf28B, CCZ1, H_NH0577018.2
  • Links
    NCBI Gene ID: 221960
    neXtProt AC: NX_P86790, NX_P86791
    UniProt: P86790

  • Chr Location
    7p22.1; chr7:6794134-6826770 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    887
  • Tissues
    30
  • cDNA Data
    80
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029617 Ensembl Gene Model | MGI Sequence Detail 26969 C57BL/6J ±  kb
transcript ENSMUST00000031621 Ensembl | MGI Sequence Detail 1769 Not Applicable  
polypeptide ENSMUSP00000031621 Ensembl | MGI Sequence Detail 480 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 81
    cDNA 81

    Microarray probesets 2
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:324480 Wu MY, et al., PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation. Autophagy. 2021 May;17(5):1096-1111
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory