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Zfp282 Gene Detail
Summary
  • Symbol
    Zfp282
  • Name
    zinc finger protein 282
  • Synonyms
    HUB1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2141413
    NCBI Gene: 101095
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:47854138-47885419 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 22.94 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    787 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2141413
 protein coding gene Chr6:47853433-47885419 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030686
 protein coding gene Chr6:46781584-46814822 (+)
A/J MGP_AJ_G0030658
 protein coding gene Chr6:44624776-44656154 (+)
AKR/J MGP_AKRJ_G0030583
 protein coding gene Chr6:46181674-46212977 (+)
BALB/cJ MGP_BALBcJ_G0030668
 protein coding gene Chr6:44978379-45010473 (+)
C3H/HeJ MGP_C3HHeJ_G0030381
 protein coding gene Chr6:46203094-46232184 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031123
 protein coding gene Chr6:47800342-47832466 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028329
 protein coding gene Chr6:42338662-42368084 (+)
CAST/EiJ MGP_CASTEiJ_G0029785
 protein coding gene Chr6:45931880-45964117 (+)
CBA/J MGP_CBAJ_G0030356
 protein coding gene Chr6:49822932-49853640 (+)
DBA/2J MGP_DBA2J_G0030505
 protein coding gene Chr6:44570553-44599562 (+)
FVB/NJ MGP_FVBNJ_G0030457
 protein coding gene Chr6:44205581-44234572 (+)
LP/J MGP_LPJ_G0030589
 protein coding gene Chr6:46679398-46709845 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030491
 protein coding gene Chr6:52699519-52731175 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031152
 protein coding gene Chr6:46093540-46122452 (+)
PWK/PhJ MGP_PWKPhJ_G0029497
 protein coding gene Chr6:44089096-44119444 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029333
 protein coding gene Chr6:45512225-45544415 (+)
WSB/EiJ MGP_WSBEiJ_G0029861
 protein coding gene Chr6:46089906-46120269 (+)



Homology
more
  • Human Ortholog
    ZNF282, zinc finger protein 282
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF282, zinc finger protein 282
  • Synonyms
    HUB1
  • Links
    NCBI Gene ID: 8427
    neXtProt AC: NX_Q9UDV7
    UniProt: Q9UDV7

  • Chr Location
    7q36.1; chr7:149195546-149226243 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Homozygous null mice show no overt abnormalities or fertility issues.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    742
  • Tissues
    27
  • cDNA Data
    64
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025821 Ensembl Gene Model | MGI Sequence Detail 31282 C57BL/6J ±  kb
transcript ENSMUST00000061890 Ensembl | MGI Sequence Detail 5573 Not Applicable  
polypeptide ENSMUSP00000053643 Ensembl | MGI Sequence Detail 666 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 65
    cDNA 64
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2141767, MGI:2442434
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:352416 Wei H, et al., A pathogenic AKAP4 variant, p.R429H, causes male in/subfertility in humans and mice. Clin Transl Med. 2023 Dec;13(12):e1463
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory