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Acp7 Gene Detail
Summary
  • Symbol
    Acp7
  • Name
    acid phosphatase 7, tartrate resistant
  • Synonyms
    C330005M16Rik, Papl
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142121
    NCBI Gene: 101744
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:28306701-28330757 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 16.86 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    746 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142121
protein coding gene Chr7:28304055-28330757 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031953
protein coding gene Chr7:27417168-27445694 (-)
A/J MGP_AJ_G0031931
protein coding gene Chr7:26745351-26769807 (-)
AKR/J MGP_AKRJ_G0031863
protein coding gene Chr7:27427131-27457862 (-)
BALB/cJ MGP_BALBcJ_G0031938
protein coding gene Chr7:26898737-26926456 (-)
C3H/HeJ MGP_C3HHeJ_G0031657
protein coding gene Chr7:27808553-27835439 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032402
protein coding gene Chr7:28291502-28319697 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029454
protein coding gene Chr7:27808028-27832980 (-)
CAST/EiJ MGP_CASTEiJ_G0030992
protein coding gene Chr7:21115056-21142211 (-)
CBA/J MGP_CBAJ_G0031623
protein coding gene Chr7:29574457-29600911 (-)
DBA/2J MGP_DBA2J_G0031775
protein coding gene Chr7:26498506-26524084 (-)
FVB/NJ MGP_FVBNJ_G0031732
protein coding gene Chr7:26575353-26598555 (-)
LP/J MGP_LPJ_G0031855
protein coding gene Chr7:27741093-27766428 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031768
protein coding gene Chr7:29057001-29084602 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032432
protein coding gene Chr7:26913998-26938474 (-)
PWK/PhJ MGP_PWKPhJ_G0030717
protein coding gene Chr7:21520047-21545751 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030550
protein coding gene Chr7:17923971-17950610 (-)
WSB/EiJ MGP_WSBEiJ_G0031101
protein coding gene Chr7:27265208-27290503 (-)



Homology
more
  • Human Ortholog
    ACP7, acid phosphatase 7, tartrate resistant (putative)
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACP7, acid phosphatase 7, tartrate resistant (putative)
  • Synonyms
    PAPL, PAPL1
  • Links
    NCBI Gene ID: 390928
    neXtProt AC: NX_Q6ZNF0
    UniProt: Q6ZNF0

  • Chr Location
    19q13.2; chr19:39083788-39111493 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037469 Ensembl Gene Model | MGI Sequence Detail 24057 C57BL/6J ±  kb
transcript ENSMUST00000040112 Ensembl | MGI Sequence Detail 1923 Not Applicable  
polypeptide ENSMUSP00000045437 Ensembl | MGI Sequence Detail 496 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000012265 acid phosphatase type 7
  • EC
  • InterPro Domains
    IPR004843 Calcineurin-like phosphoesterase domain, ApaH type
    IPR025733 Iron/zinc purple acid phosphatase-like C-terminal domain
    IPR029052 Metallo-dependent phosphatase-like
    IPR008963 Purple acid phosphatase-like, N-terminal
    IPR041792 Purple acid phosphatase, metallophosphatase domain
    IPR015914 Purple acid phosphatase, N-terminal
  • GlyGen
    Q8BX37 3 sites, 1 N-linked glycan (1 site)
Molecular
Reagents
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  • All nucleic 11
    cDNA 11

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory