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Enkd1 Gene Detail
Summary
  • Symbol
    Enkd1
  • Name
    enkurin domain containing 1
  • Synonyms
    E130303B06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142593
    NCBI Gene: 102124
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:106430283-106434842 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 53.04 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    163 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142593
 protein coding gene Chr8:106430281-106435358 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034056
 protein coding gene Chr8:108006959-108011237 (-)
A/J MGP_AJ_G0034037
 protein coding gene Chr8:103690029-103694385 (-)
AKR/J MGP_AKRJ_G0033963
 protein coding gene Chr8:106690832-106695110 (-)
BALB/cJ MGP_BALBcJ_G0034030
 protein coding gene Chr8:103880391-103884664 (-)
C3H/HeJ MGP_C3HHeJ_G0033742
 protein coding gene Chr8:107431609-107436547 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034550
 protein coding gene Chr8:111974363-111978638 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031492
 protein coding gene Chr8:96828067-96832340 (-)
CAST/EiJ MGP_CASTEiJ_G0033068
 protein coding gene Chr8:106931484-106935787 (-)
CBA/J MGP_CBAJ_G0033715
 protein coding gene Chr8:115567833-115574751 (-)
DBA/2J MGP_DBA2J_G0033870
 protein coding gene Chr8:103037581-103041860 (-)
FVB/NJ MGP_FVBNJ_G0033816
 protein coding gene Chr8:101966050-101970326 (-)
LP/J MGP_LPJ_G0033961
 protein coding gene Chr8:108213628-108217905 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033859
 protein coding gene Chr8:118765296-118770416 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034568
 protein coding gene Chr8:106654781-106659065 (-)
PWK/PhJ MGP_PWKPhJ_G0032769
 protein coding gene Chr8:102427966-102432419 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032610
 protein coding gene Chr8:105339880-105346476 (-)
WSB/EiJ MGP_WSBEiJ_G0033184
 protein coding gene Chr8:107324422-107328694 (-)



Homology
more
  • Human Ortholog
    ENKD1, enkurin domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ENKD1, enkurin domain containing 1
  • Synonyms
    C16orf48, DAKV6410, FBB11
  • Links
    NCBI Gene ID: 84080
    neXtProt AC: NX_Q9H0I2
    UniProt: Q9H0I2

  • Chr Location
    16q22.1; chr16:67662945-67667265 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice exhibit ciliogenesis defects in multiple organs, defective vision, and moderately altered cardiac muscle conduction.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    779
  • Tissues
    21
  • cDNA Data
    18
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000013155 Ensembl Gene Model | MGI Sequence Detail 4560 C57BL/6J ±  kb
    transcript ENSMUST00000013299 Ensembl | MGI Sequence Detail 1275 Not Applicable  
    polypeptide ENSMUSP00000013299 Ensembl | MGI Sequence Detail 346 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 18
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 3
      Gene Ontology 6
      Phenotypes 9
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory