About   Help   FAQ
Zfp365 Gene Detail
Summary
  • Symbol
    Zfp365
  • Name
    zinc finger protein 365
  • Synonyms
    DBZ, mKIAA0844, Su48
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143676
    NCBI Gene: 216049
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:67721935-67748492 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 35.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    899 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143676
 protein coding gene Chr10:67721933-67748492 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017327
 protein coding gene Chr10:67675532-67702040 (-)
A/J MGP_AJ_G0017304
 protein coding gene Chr10:65404289-65430820 (-)
AKR/J MGP_AKRJ_G0017265
 protein coding gene Chr10:67187270-67214243 (-)
BALB/cJ MGP_BALBcJ_G0017264
 protein coding gene Chr10:65612876-65639415 (-)
C3H/HeJ MGP_C3HHeJ_G0017088
 protein coding gene Chr10:67188041-67214617 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017722
 protein coding gene Chr10:70107419-70135782 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015412
 protein coding gene Chr10:62090621-62117380 (-)
CAST/EiJ MGP_CASTEiJ_G0016658
 protein coding gene Chr10:67244965-67271622 (-)
CBA/J MGP_CBAJ_G0017060
 protein coding gene Chr10:72786485-72813044 (-)
DBA/2J MGP_DBA2J_G0017165
 protein coding gene Chr10:64787811-64814285 (-)
FVB/NJ MGP_FVBNJ_G0017158
 protein coding gene Chr10:63946901-63976560 (-)
LP/J MGP_LPJ_G0017238
 protein coding gene Chr10:68086396-68117254 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017186
 protein coding gene Chr10:74985102-75014170 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017761
 protein coding gene Chr10:67085629-67112197 (-)
PWK/PhJ MGP_PWKPhJ_G0016442
 protein coding gene Chr10:64590362-64617445 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016224
 protein coding gene Chr10:66464628-66493304 (-)
WSB/EiJ MGP_WSBEiJ_G0016722
 protein coding gene Chr10:67026315-67053731 (-)



Homology
more
  • Human Ortholog
    ZNF365, zinc finger protein 365
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF365, zinc finger protein 365
  • Synonyms
    Su48, UAN, ZNF365D
  • Links
    NCBI Gene ID: 22891
    neXtProt AC: NX_Q70YC4, NX_Q70YC5
    UniProt: Q70YC4, Q70YC5

  • Chr Location
    10q21.2; chr10:62374192-62480288 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ZNF365 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit abnormal cortical basket cells in the somatosensory cortices, delayed myelination in the corpus callosum during the early postnatal period, and an increase in immature oligodendrocytes.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    737
  • Tissues
    18
  • cDNA Data
    41
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 216049 NCBI Gene Model | MGI Sequence Detail 26558 C57BL/6J ±  kb
    transcript NM_178679 RefSeq | MGI Sequence Detail 4279 C57BL/6  
    polypeptide Q8BG89 UniProt | EBI | MGI Sequence Detail 408 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 45
      cDNA 41
      Primer pair 4

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2143789
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 6
      Gene Ontology 10
      Phenotypes 18
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory