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Zfr2 Gene Detail
Summary
  • Symbol
    Zfr2
  • Name
    zinc finger RNA binding protein 2
  • Synonyms
    2010013I23Rik, 9130206N08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143792
    NCBI Gene: 103406
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:81068989-81087957 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    453 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143792
 protein coding gene Chr10:81068967-81087957 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017544
 protein coding gene Chr10:81934284-81955503 (+)
A/J MGP_AJ_G0017522
 protein coding gene Chr10:79036243-79055153 (+)
AKR/J MGP_AKRJ_G0017483
 protein coding gene Chr10:81209878-81228809 (+)
BALB/cJ MGP_BALBcJ_G0017484
 protein coding gene Chr10:79254742-79274434 (+)
C3H/HeJ MGP_C3HHeJ_G0017307
 protein coding gene Chr10:81302242-81322204 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017938
 protein coding gene Chr10:84751326-84772691 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015627
 protein coding gene Chr10:75233735-75253267 (+)
CAST/EiJ MGP_CASTEiJ_G0016874
 protein coding gene Chr10:81532093-81553245 (+)
CBA/J MGP_CBAJ_G0017279
 protein coding gene Chr10:88056603-88079280 (+)
DBA/2J MGP_DBA2J_G0017385
 protein coding gene Chr10:78241494-78260580 (+)
FVB/NJ MGP_FVBNJ_G0017379
 protein coding gene Chr10:77485689-77506413 (+)
LP/J MGP_LPJ_G0017456
 protein coding gene Chr10:82389433-82410054 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017405
 protein coding gene Chr10:89912869-89932753 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017979
 protein coding gene Chr10:81212088-81232489 (+)
PWK/PhJ MGP_PWKPhJ_G0016655
 protein coding gene Chr10:78133439-78152563 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016445
 protein coding gene Chr10:80160253-80179318 (+)
WSB/EiJ MGP_WSBEiJ_G0016934
 protein coding gene Chr10:81241380-81261696 (+)



Homology
more
  • Human Ortholog
    ZFR2, zinc finger RNA binding protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZFR2, zinc finger RNA binding protein 2
  • Synonyms
    KIAA1086
  • Links
    NCBI Gene ID: 23217
    neXtProt AC: NX_Q9UPR6
    UniProt: Q9UPR6

  • Chr Location
    19p13.3; chr19:3804024-3869038 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • cDNA Data
    7
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034949 Ensembl Gene Model | MGI Sequence Detail 18969 C57BL/6J ±  kb
transcript ENSMUST00000117798 Ensembl | MGI Sequence Detail 3349 Not Applicable  
polypeptide ENSMUSP00000113913 Ensembl | MGI Sequence Detail 874 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 3
Other
Accession IDs
less
MGI:1919328
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:326370 Cauchi LM, et al., Zinc finger RNA binding protein 2 (ZFR2) is not required for male fertility in the mouse. Dev Biol. 2022 Jun 6;489:55-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory