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Ighg Gene Detail
Summary
  • Symbol
    Ighg
  • Name
    Immunoglobulin heavy chain (gamma polypeptide)
  • Feature Type
    gene segment
  • IDs
    MGI:2144967
    NCBI Gene: 380794
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:113266587-113896029 bp, - strand
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 62.10 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    10880 from dbSNP Build 142
  • Strain Annotations
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2144967
 gene segment Chr12:113266587-113896029 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IGHG1, immunoglobulin heavy constant gamma 1 (G1m marker)
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGHG1, immunoglobulin heavy constant gamma 1 (G1m marker)
  • Links
    NCBI Gene ID: 3500
    UniProt: P01857

  • Chr Location
    14q32.33; chr14:105736343-105743071 (-)  GRCh38
  • Human Ortholog
    IGHG2, immunoglobulin heavy constant gamma 2 (G2m marker)
  • Links
    NCBI Gene ID: 3501
    UniProt: P01859

  • Chr Location
    14q32.33; chr14:105639559-105644790 (-)  GRCh38
  • Human Ortholog
    IGHG3, immunoglobulin heavy constant gamma 3 (G3m marker)
  • Synonyms
    IgG3
  • Links
    NCBI Gene ID: 3502
    UniProt: P01860

  • Chr Location
    14q32.33; chr14:105764503-105771405 (-)  GRCh38
  • Human Ortholog
    IGHG4, immunoglobulin heavy constant gamma 4 (G4m marker)
  • Links
    NCBI Gene ID: 3503
    UniProt: P01861

  • Chr Location
    14q32.33; chr14:105620506-105626066 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    12
Sequences &
Gene Models
less
  • All Sequences
    27
  • RefSeq
    1
  • UniProt
    4
Representative SequencesLengthStrain/SpeciesFlank
genomic D78344 GenBank | ENA | DDBJ | MGI Sequence Detail 59641 BALB/c ±  kb
transcript AK135975 GenBank | ENA | DDBJ | MGI Sequence Detail 1889 C57BL/6J  
polypeptide P01863 UniProt | EBI | MGI Sequence Detail 330 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    Genomic 5
    cDNA 12

    Microarray probesets 3
References
more
  • Summaries
    All 20
    Gene Ontology 3
  • Earliest
    J:32622 Tucker PW, et al., Structure of the constant and 3' untranslated regions of the murine gamma 2b heavy chain messenger RNA. Science. 1979 Dec 14;206(4424):1299-303
  • Latest
    J:221557 Nayak DK, et al., Channel catfish soluble FcmuR binds conserved linear epitopes present on Cmu3 and Cmu4. Mol Immunol. 2010 Mar;47(6):1306-16
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory