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Rmdn2 Gene Detail
Summary
  • Symbol
    Rmdn2
  • Name
    regulator of microtubule dynamics 2
  • Synonyms
    Fam82a1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147043
    NCBI Gene: 381110
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:79919292-80000621 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 50.30 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2175 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147043
 protein coding gene Chr17:79886025-80000630 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024051
 protein coding gene Chr17:82487633-82549241 (+)
A/J MGP_AJ_G0024008
 protein coding gene Chr17:79953145-80016953 (+)
AKR/J MGP_AKRJ_G0023977
 protein coding gene Chr17:81173322-81237440 (+)
BALB/cJ MGP_BALBcJ_G0024010
 protein coding gene Chr17:79829582-79892675 (+)
C3H/HeJ MGP_C3HHeJ_G0023774
 protein coding gene Chr17:82080691-82142485 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024454
 protein coding gene Chr17:85503186-85563584 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021896
 protein coding gene Chr17:75343766-75401484 (+)
CAST/EiJ MGP_CASTEiJ_G0023254
 protein coding gene Chr17:82715656-82779141 (+)
CBA/J MGP_CBAJ_G0023748
 protein coding gene Chr17:89051982-89120637 (+)
DBA/2J MGP_DBA2J_G0023877
 protein coding gene Chr17:78479694-78537837 (+)
FVB/NJ MGP_FVBNJ_G0023843
 protein coding gene Chr17:77976710-78036052 (+)
LP/J MGP_LPJ_G0023960
 protein coding gene Chr17:83332913-83396861 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023871
 protein coding gene Chr17:89140378-89197172 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024499
 protein coding gene Chr17:81654628-81720185 (+)
PWK/PhJ MGP_PWKPhJ_G0023000
 protein coding gene Chr17:77977222-78037670 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022811
 protein coding gene Chr17:78425352-78489065 (+)
WSB/EiJ MGP_WSBEiJ_G0023321
 protein coding gene Chr17:82480511-82542800 (+)



Homology
more
  • Human Ortholog
    RMDN2, regulator of microtubule dynamics 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RMDN2, regulator of microtubule dynamics 2
  • Synonyms
    BLOCK18, FAM82A, FAM82A1, PRO34163, PYST9371, RMD-2, RMD2, RMD4
  • Links
    NCBI Gene ID: 151393
    neXtProt AC: NX_Q96LZ7
    UniProt: Q96LZ7

  • Chr Location
    2p22.2; chr2:37920901-38067142 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    750
  • Tissues
    5
  • cDNA Data
    17
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036368 Ensembl Gene Model | MGI Sequence Detail 81330 C57BL/6J ±  kb
transcript ENSMUST00000225357 Ensembl | MGI Sequence Detail 2118 Not Applicable  
polypeptide ENSMUSP00000153443 Ensembl | MGI Sequence Detail 410 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000030940 regulator of microtubule dynamics protein 2
    (term hierarchy)
  • InterPro Domains
    IPR049039 Regulator of microtubule dynamics protein 1-3, alpha helical repeats
    IPR011990 Tetratricopeptide-like helical domain superfamily
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 5
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 2
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:237827 Gineste C, et al., In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype. Neuromuscul Disord. 2013 Apr;23(4):357-69
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory