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Kank1 Gene Detail
Summary
  • Symbol
    Kank1
  • Name
    KN motif and ankyrin repeat domains 1
  • Synonyms
    A930031B09Rik, Ankrd15, D330024H06Rik, mKIAA0172
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147707
    NCBI Gene: 107351
  • Alliance
    gene page
  • Transcription Start Sites
    22 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:25214339-25411860 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 20.33 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6585 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147707
 protein coding gene Chr19:25214146-25411861 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025001
 protein coding gene Chr19:23519856-23726533 (+)
A/J MGP_AJ_G0024978
 protein coding gene Chr19:22232314-22436257 (+)
AKR/J MGP_AKRJ_G0024946
 protein coding gene Chr19:23047909-23265318 (+)
BALB/cJ MGP_BALBcJ_G0024977
 protein coding gene Chr19:22280468-22483073 (+)
C3H/HeJ MGP_C3HHeJ_G0024733
 protein coding gene Chr19:23047274-23258852 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025418
 protein coding gene Chr19:24243106-24454077 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022837
 protein coding gene Chr19:22373229-22568464 (+)
CAST/EiJ MGP_CASTEiJ_G0024203
 protein coding gene Chr19:22793612-23006058 (+)
CBA/J MGP_CBAJ_G0024711
 protein coding gene Chr19:25263243-25503491 (+)
DBA/2J MGP_DBA2J_G0024843
 protein coding gene Chr19:22227835-22431530 (+)
FVB/NJ MGP_FVBNJ_G0024805
 protein coding gene Chr19:22130138-22332207 (+)
LP/J MGP_LPJ_G0024928
 protein coding gene Chr19:23459392-23667038 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024832
 protein coding gene Chr19:25308769-25517760 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025473
 protein coding gene Chr19:23088368-23304464 (+)
PWK/PhJ MGP_PWKPhJ_G0023951
 protein coding gene Chr19:21854011-22055031 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023756
 protein coding gene Chr19:22330790-22546533 (+)
WSB/EiJ MGP_WSBEiJ_G0024270
 protein coding gene Chr19:23117786-23326868 (+)



Homology
more
  • Human Ortholog
    KANK1, KN motif and ankyrin repeat domains 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KANK1, KN motif and ankyrin repeat domains 1
  • Synonyms
    ANKRD15, CPSQ2, KANK
  • Links
    NCBI Gene ID: 23189
    neXtProt AC: NX_Q14678
    UniProt: Q14678

  • Chr Location
    9p24.3; chr9:470291-746105 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human KANK1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1206
  • Tissues
    103
  • cDNA Data
    70
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032702 Ensembl Gene Model | MGI Sequence Detail 197522 C57BL/6J ±  kb
    transcript ENSMUST00000049400 Ensembl | MGI Sequence Detail 5637 Not Applicable  
    polypeptide ENSMUSP00000042177 Ensembl | MGI Sequence Detail 1360 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 70
      cDNA 70

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1925073, MGI:2147636
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 7
      Gene Ontology 3
      Phenotypes 14
    • Earliest
      J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
    • Latest
      J:354142 Oda K, et al., The Protective Role of KANK1 in Podocyte Injury. Int J Mol Sci. 2024 May 27;25(11)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory