About   Help   FAQ
Nudt10 Gene Detail
Summary
  • Symbol
    Nudt10
  • Name
    nudix hydrolase 10
  • Synonyms
    Dipp3a, DIPP3 alpha, nudix (nucleoside diphosphate linked moiety X)-type motif 10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147931
    NCBI Gene: 102954
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:6080750-6085069 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 2.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    97 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147931
 protein coding gene ChrX:6080750-6085321 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035503
 protein coding gene ChrX:775402-779731 (-)
A/J MGP_AJ_G0035481
 protein coding gene ChrX:774751-779069 (-)
AKR/J MGP_AKRJ_G0035414
 protein coding gene ChrX:790659-794847 (-)
BALB/cJ MGP_BALBcJ_G0035477
 protein coding gene ChrX:785815-790136 (-)
C3H/HeJ MGP_C3HHeJ_G0035185
 protein coding gene ChrX:791274-795684 (-)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0034485
 protein coding gene ChrX:714466-747196 (-)
CBA/J MGP_CBAJ_G0035155
 protein coding gene ChrX:883560-887808 (-)
DBA/2J MGP_DBA2J_G0035312
 protein coding gene ChrX:799950-804254 (-)
FVB/NJ MGP_FVBNJ_G0035259
 protein coding gene ChrX:765623-774036 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0035298
 protein coding gene ChrX:841133-851070 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036019
 protein coding gene ChrX:760439-764863 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0034024
 protein coding gene ChrX:731001-734902 (-)
WSB/EiJ MGP_WSBEiJ_G0034608
 protein coding gene ChrX:790540-794850 (-)



Homology
more
  • Human Ortholog
    NUDT10, nudix hydrolase 10
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NUDT10, nudix hydrolase 10
  • Synonyms
    APS2, DIPP3a, DIPP3-alpha
  • Links
    NCBI Gene ID: 170685
    neXtProt AC: NX_Q8NFP7
    UniProt: Q8NFP7

  • Chr Location
    Xp11.22; chrX:51332231-51337525 (+)  GRCh38
  • Human Ortholog
    NUDT11, nudix hydrolase 11
  • Synonyms
    APS1, ASP1, DIPP3b, DIPP3beta, hDIPP3beta
  • Links
    NCBI Gene ID: 55190
    neXtProt AC: NX_Q96G61
    UniProt: Q96G61

  • Chr Location
    Xp11.22; chrX:51490011-51496592 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype reference
Male mice hemizygous for a null allele exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073293 Ensembl Gene Model | MGI Sequence Detail 4320 C57BL/6J ±  kb
transcript ENSMUST00000103006 Ensembl | MGI Sequence Detail 1775 Not Applicable  
polypeptide ENSMUSP00000100071 Ensembl | MGI Sequence Detail 164 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • GlyGen
    P0C027 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 3
References
more
  • Summaries
    All 23
    Gene Ontology 6
    Phenotypes 1
  • Earliest
    J:84307 Hua LV, et al., Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases. Biochem J. 2003 Jul 1;373(Pt 1):81-9
  • Latest
    J:279039 Lu Y, et al., CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice. Biol Reprod. 2019 Aug 1;101(2):501-511
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory