About   Help   FAQ
Jade3 Gene Detail
Summary
  • Symbol
    Jade3
  • Name
    jade family PHD finger 3
  • Synonyms
    mKIAA0215, Phf16
  • Feature Type
    protein coding gene
  • IDs
    MGI:2148019
    NCBI Gene: 382207
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:20291927-20386178 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 15.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1502 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2148019
 protein coding gene ChrX:20291611-20386178 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035590
 protein coding gene ChrX:15306899-15410545 (+)
A/J MGP_AJ_G0035567
 protein coding gene ChrX:15405907-15500179 (+)
AKR/J MGP_AKRJ_G0035500
 protein coding gene ChrX:15914264-16012494 (+)
BALB/cJ MGP_BALBcJ_G0035560
 protein coding gene ChrX:15155853-15253136 (+)
C3H/HeJ MGP_C3HHeJ_G0035278
 protein coding gene ChrX:15507081-15621945 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036096
 protein coding gene ChrX:15713282-15810796 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032960
 protein coding gene ChrX:13655526-13743699 (+)
CAST/EiJ MGP_CASTEiJ_G0034569
 protein coding gene ChrX:14833028-14922233 (+)
CBA/J MGP_CBAJ_G0035247
 protein coding gene ChrX:16432089-16539992 (+)
DBA/2J MGP_DBA2J_G0035399
 protein coding gene ChrX:15205428-15301834 (+)
FVB/NJ MGP_FVBNJ_G0035345
 protein coding gene ChrX:15111621-15203217 (+)
LP/J MGP_LPJ_G0035481
 protein coding gene ChrX:15540411-15637844 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035389
 protein coding gene ChrX:16692727-16796114 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036103
 protein coding gene ChrX:15224688-15326832 (+)
PWK/PhJ MGP_PWKPhJ_G0034270
 protein coding gene ChrX:14403111-14492460 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034110
 protein coding gene ChrX:15202990-15301527 (+)
WSB/EiJ MGP_WSBEiJ_G0034704
 protein coding gene ChrX:15101578-15194227 (+)



Homology
more
  • Human Ortholog
    JADE3, jade family PHD finger 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    JADE3, jade family PHD finger 3
  • Synonyms
    JADE-3, PHF16
  • Links
    NCBI Gene ID: 9767
    neXtProt AC: NX_Q92613
    UniProt: Q92613

  • Chr Location
    Xp11.3; chrX:46912276-47061242 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    10 images
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male chimeras hemizygous for a gene trapped allele appear normal at E9.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    825
  • Tissues
    109
  • cDNA Data
    35
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000037315 Ensembl Gene Model | MGI Sequence Detail 94252 C57BL/6J ±  kb
    transcript ENSMUST00000115384 Ensembl | MGI Sequence Detail 4866 Not Applicable  
    polypeptide ENSMUSP00000111042 Ensembl | MGI Sequence Detail 823 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 36
      cDNA 35
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2147927
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:86562 Tzouanacou E, et al., Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development. Mol Cell Biol. 2003 Dec;23(23):8553-2
    • Latest
      J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory