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Gtf2ird2 Gene Detail
Summary
  • Symbol
    Gtf2ird2
  • Name
    GTF2I repeat domain containing 2
  • Synonyms
    1700012P16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2149780
    NCBI Gene: 114674
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:134211629-134246988 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 74.45 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1248 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2149780
 protein coding gene Chr5:134211629-134253209 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030153
 protein coding gene Chr5:138555460-138595694 (+)
A/J MGP_AJ_G0030121
 protein coding gene Chr5:132685091-132726142 (+)
AKR/J MGP_AKRJ_G0030054
 protein coding gene Chr5:136964635-137005615 (+)
BALB/cJ MGP_BALBcJ_G0030131
 protein coding gene Chr5:134016915-134058620 (+)
C3H/HeJ MGP_C3HHeJ_G0029847
 protein coding gene Chr5:137515125-137555675 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030584
 protein coding gene Chr5:143781430-143823832 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027808
 protein coding gene Chr5:126960716-127000564 (+)
CAST/EiJ MGP_CASTEiJ_G0029256
 protein coding gene Chr5:136957706-137002346 (+)
CBA/J MGP_CBAJ_G0029817
 protein coding gene Chr5:149377085-149417379 (+)
DBA/2J MGP_DBA2J_G0029968
 protein coding gene Chr5:132588934-132629272 (+)
FVB/NJ MGP_FVBNJ_G0029924
 protein coding gene Chr5:131715293-131757790 (+)
LP/J MGP_LPJ_G0030056
 protein coding gene Chr5:139036221-139079819 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029955
 protein coding gene Chr5:152489567-152533143 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030624
 protein coding gene Chr5:136704268-136746631 (+)
PWK/PhJ MGP_PWKPhJ_G0028971
 protein coding gene Chr5:131599711-131643379 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028806
 protein coding gene Chr5:134272626-134312459 (+)
WSB/EiJ MGP_WSBEiJ_G0029330
 protein coding gene Chr5:137439715-137480911 (+)



Homology
more
  • Human Ortholog
    GTF2IRD2, GTF2I repeat domain containing 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GTF2IRD2, GTF2I repeat domain containing 2
  • Synonyms
    FP630, GTF2IRD2A, GTF2IRD2 alpha
  • Links
    NCBI Gene ID: 84163
    neXtProt AC: NX_Q86UP8
    UniProt: Q86UP8

  • Chr Location
    7q11.23; chr7:74796151-74851605 (-)  GRCh38
  • Human Ortholog
    GTF2IRD2B, GTF2I repeat domain containing 2B
  • Synonyms
    GTF2IRD2, GTF2IRD2A
  • Links
    NCBI Gene ID: 389524
    neXtProt AC: NX_Q6EKJ0
    UniProt: Q6EKJ0

  • Chr Location
    7q11.23; chr7:75092556-75149817 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    739
  • Tissues
    23
  • cDNA Data
    25
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 114674 NCBI Gene Model | MGI Sequence Detail 35360 C57BL/6J ±  kb
transcript NM_053266 RefSeq | MGI Sequence Detail 3468 C57BL/6  
polypeptide Q99NI3 UniProt | EBI | MGI Sequence Detail 936 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000034127 general transcription factor II-I repeat domain-containing protein 2
    (term hierarchy)
  • InterPro Domains
    IPR042224 General transcription factor II-I repeat domain-containing protein 2
    IPR004212 GTF2I-like repeat
    IPR036647 GTF2I-like repeat superfamily
    IPR040647 SPIN-DOC-like, zinc-finger
Molecular
Reagents
less
  • All nucleic 26
    cDNA 25
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory