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Cts3 Gene Detail
Summary
  • Symbol
    Cts3
  • Name
    cathepsin 3
  • Synonyms
    1600000I23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2151929
    NCBI Gene: 117066
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:61712444-61717941 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 32.74 cM, cytoband B3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    204 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2151929
 protein coding gene Chr13:61712444-61717984 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020663
 protein coding gene Chr13:61395000-61402750 (-)
A/J MGP_AJ_G0020617
 protein coding gene Chr13:59147409-59153012 (-)
AKR/J MGP_AKRJ_G0020593
 protein coding gene Chr13:60871674-60877170 (-)
BALB/cJ MGP_BALBcJ_G0020614
 protein coding gene Chr13:59349678-59355168 (-)
C3H/HeJ MGP_C3HHeJ_G0020411
 protein coding gene Chr13:60639389-60644885 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021048
 protein coding gene Chr13:63229052-63234548 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018629
 protein coding gene Chr13:56873820-56879390 (-)
CAST/EiJ MGP_CASTEiJ_G0019927
 protein coding gene Chr13:60868898-60874321 (-)
CBA/J MGP_CBAJ_G0020371
 protein coding gene Chr13:65567881-65573377 (-)
DBA/2J MGP_DBA2J_G0020495
 protein coding gene Chr13:58623925-58629421 (-)
FVB/NJ MGP_FVBNJ_G0020473
 protein coding gene Chr13:58116030-58121538 (-)
LP/J MGP_LPJ_G0020571
 protein coding gene Chr13:61580928-61586432 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020503
 protein coding gene Chr13:64831929-64841293 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021091
 protein coding gene Chr13:60422169-60427665 (-)
PWK/PhJ MGP_PWKPhJ_G0019680
 protein coding gene Chr13:58685731-58691475 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019509
 protein coding gene Chr13:59346498-59352557 (-)
WSB/EiJ MGP_WSBEiJ_G0019988
 protein coding gene Chr13:60968577-60979901 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    750
  • Tissues
    30
  • cDNA Data
    44
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074870 Ensembl Gene Model | MGI Sequence Detail 5498 C57BL/6J ±  kb
transcript ENSMUST00000223815 Ensembl | MGI Sequence Detail 1367 Not Applicable  
polypeptide ENSMUSP00000153399 Ensembl | MGI Sequence Detail 332 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR013201 Cathepsin propeptide inhibitor domain (I29)
    IPR025660 Cysteine peptidase, histidine active site
    IPR039417 Papain-like cysteine endopeptidase
    IPR038765 Papain-like cysteine peptidase superfamily
    IPR013128 Peptidase C1A
    IPR000668 Peptidase C1A, papain C-terminal
Molecular
Reagents
less
  • All nucleic 47
    cDNA 45
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916256
References
more
  • Summaries
    All 28
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:209833 Kim J, et al., Peg3 mutational effects on reproduction and placenta-specific gene families. PLoS One. 2013;8(12):e83359
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory