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Tshz2 Gene Detail
Summary
  • Symbol
    Tshz2
  • Name
    teashirt zinc finger family member 2
  • Synonyms
    2900073F20Rik, Mtsh2, Sdccag33l, teashirt2, Tsh2, Zfp218
  • Feature Type
    protein coding gene
  • IDs
    MGI:2153084
    NCBI Gene: 228911
  • Alliance
    gene page
  • Transcription Start Sites
    21 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:169474933-169913736 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 89.47 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    13578 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2153084
 protein coding gene Chr2:169474430-169914671 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026932
 protein coding gene Chr2:175617896-176085971 (+)
A/J MGP_AJ_G0026899
 protein coding gene Chr2:168288691-168733979 (+)
AKR/J MGP_AKRJ_G0026870
 protein coding gene Chr2:173333753-173794202 (+)
BALB/cJ MGP_BALBcJ_G0026908
 protein coding gene Chr2:168667058-169111195 (+)
C3H/HeJ MGP_C3HHeJ_G0026650
 protein coding gene Chr2:173712486-174168354 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027355
 protein coding gene Chr2:180692794-181157755 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024725
 protein coding gene Chr2:161599191-162040405 (+)
CAST/EiJ MGP_CASTEiJ_G0026108
 protein coding gene Chr2:174251673-174729364 (+)
CBA/J MGP_CBAJ_G0026627
 protein coding gene Chr2:187406458-187909284 (+)
DBA/2J MGP_DBA2J_G0026765
 protein coding gene Chr2:167390177-167831652 (+)
FVB/NJ MGP_FVBNJ_G0026731
 protein coding gene Chr2:165979499-166430212 (+)
LP/J MGP_LPJ_G0026866
 protein coding gene Chr2:175587080-176058378 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026750
 protein coding gene Chr2:190569725-191037740 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027412
 protein coding gene Chr2:173271564-173734872 (+)
PWK/PhJ MGP_PWKPhJ_G0025845
 protein coding gene Chr2:167092132-167544675 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025645
 protein coding gene Chr2:172267981-172743226 (+)
WSB/EiJ MGP_WSBEiJ_G0026181
 protein coding gene Chr2:174211136-174674633 (+)



Homology
more
  • Human Ortholog
    TSHZ2, teashirt zinc finger homeobox 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TSHZ2, teashirt zinc finger homeobox 2
  • Synonyms
    C20orf17, OVC10-2, TSH2, ZABC2, ZNF218
  • Links
    NCBI Gene ID: 128553
    neXtProt AC: NX_Q9NRE2
    UniProt: Q9NRE2

  • Chr Location
    20q13.2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a transposon induced allele die in utero; cultured blastocysts fail to hatch.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    777
  • Tissues
    42
  • cDNA Data
    20
  • Literature Summary
    18
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047907 Ensembl Gene Model | MGI Sequence Detail 438804 C57BL/6J ±  kb
transcript ENSMUST00000109159 Ensembl | MGI Sequence Detail 4314 Not Applicable  
polypeptide ENSMUSP00000104787 Ensembl | MGI Sequence Detail 1030 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 21
    Primer pair 1
    Other 2

    Microarray probesets 7
Other
Accession IDs
less
MGI:1920238
References
more
  • Summaries
    All 56
    Developmental Gene Expression 18
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:72479 Caubit X, et al., Vertebrate orthologues of the Drosophila region-specific patterning gene teashirt. Mech Dev. 2000 Mar 1;91(1-2):445-8
  • Latest
    J:354191 Kc R, et al., Multimodal Hox5 activity generates motor neuron diversity. Commun Biol. 2024 Sep 17;7(1):1166
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory