About   Help   FAQ
Pramel7 Gene Detail
Summary
  • Symbol
    Pramel7
  • Name
    PRAME like 7
  • Feature Type
    protein coding gene
  • IDs
    MGI:2156391
    NCBI Gene: 347712
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr2:87319432-87322762 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 49.86 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    214 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2156391
 protein coding gene Chr2:87319431-87327437 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026010
 protein coding gene Chr2:88541870-88549802 (-)
A/J MGP_AJ_G0025979
 protein coding gene Chr2:84998325-85007261 (-)
AKR/J MGP_AKRJ_G0025951
 protein coding gene Chr2:87334695-87343959 (-)
BALB/cJ MGP_BALBcJ_G0025982
 protein coding gene Chr2:85195126-85203184 (-)
C3H/HeJ MGP_C3HHeJ_G0025737
 protein coding gene Chr2:87551314-87562889 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026429
 protein coding gene Chr2:91469182-91479350 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023827
 protein coding gene Chr2:81698836-81702200 (-)
CAST/EiJ MGP_CASTEiJ_G0025198
 protein coding gene Chr2:88027636-88035550 (-)
CBA/J MGP_CBAJ_G0025717
 protein coding gene Chr2:94518747-94526521 (-)
DBA/2J MGP_DBA2J_G0025848
 protein coding gene Chr2:84592373-84601387 (-)
FVB/NJ MGP_FVBNJ_G0025812
 protein coding gene Chr2:83700327-83708699 (-)
LP/J MGP_LPJ_G0025949
 protein coding gene Chr2:88559122-88568469 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025840
 protein coding gene Chr2:97303283-97312942 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026482
 protein coding gene Chr2:87456520-87465444 (-)
PWK/PhJ MGP_PWKPhJ_G0024940
 protein coding gene Chr2:84506548-84517653 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024746
 protein coding gene Chr2:87479017-87490104 (-)
WSB/EiJ MGP_WSBEiJ_G0025274
 protein coding gene Chr2:88170284-88178255 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    753
  • Tissues
    6
  • cDNA Data
    26
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 347712 NCBI Gene Model | MGI Sequence Detail 3331 C57BL/6J ±  kb
transcript NM_178250 RefSeq | MGI Sequence Detail 1860 Not Specified  
polypeptide Q810Y8 UniProt | EBI | MGI Sequence Detail 479 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR032675 Leucine-rich repeat domain superfamily
    IPR026271 PRAME
    IPR050694 PRAME domain-containing protein
Molecular
Reagents
less
  • All nucleic 28
    cDNA 26
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:82465 Bortvin A, et al., Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei. Development. 2003 Apr;130(8):1673-80
  • Latest
    J:243489 Graf U, et al., Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways. Nat Cell Biol. 2017 Jul;19(7):763-773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory