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Or51e2 Gene Detail
Summary
  • Symbol
    Or51e2
  • Name
    olfactory receptor family 51 subfamily E member 2
  • Synonyms
    4633402A21Rik, GA_x6K02T2PBJ9-5459657-5458695, MOL2.3, MOR18-2, Olfr78, PSGR, RA1c
  • Feature Type
    protein coding gene
  • IDs
    MGI:2157548
    NCBI Gene: 170639
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:102389928-102408678 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 54.83 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    570 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2157548
 protein coding gene Chr7:102387718-102408678 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032625
 protein coding gene Chr7:105813604-105832350 (-)
A/J MGP_AJ_G0032603
 protein coding gene Chr7:103100868-103120564 (-)
AKR/J MGP_AKRJ_G0032539
 protein coding gene Chr7:105585329-105604075 (-)
BALB/cJ MGP_BALBcJ_G0032614
 protein coding gene Chr7:102803165-102822584 (-)
C3H/HeJ MGP_C3HHeJ_G0032327
 protein coding gene Chr7:105978111-105996859 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033111
 protein coding gene Chr7:109771988-109792578 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030105
 protein coding gene Chr7:105435777-105454146 (-)
CAST/EiJ MGP_CASTEiJ_G0031654
 protein coding gene Chr7:97525853-97546953 (-)
CBA/J MGP_CBAJ_G0032293
 protein coding gene Chr7:113643732-113667988 (-)
DBA/2J MGP_DBA2J_G0032446
 protein coding gene Chr7:101435108-101454248 (-)
FVB/NJ MGP_FVBNJ_G0032400
 protein coding gene Chr7:101193650-101213403 (-)
LP/J MGP_LPJ_G0032535
 protein coding gene Chr7:107139279-107158734 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032436
 protein coding gene Chr7:114923014-114946757 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033133
 protein coding gene Chr7:104847377-104865995 (-)
PWK/PhJ MGP_PWKPhJ_G0031372
 protein coding gene Chr7:94532933-94552660 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031212
 protein coding gene Chr7:92150308-92169496 (-)
WSB/EiJ MGP_WSBEiJ_G0031770
 protein coding gene Chr7:105528262-105547921 (-)



Homology
more
  • Human Ortholog
    OR51E2, olfactory receptor family 51 subfamily E member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OR51E2, olfactory receptor family 51 subfamily E member 2
  • Synonyms
    HPRAJ, OR51E3P, OR52A2, PSGR
  • Links
    NCBI Gene ID: 81285
    neXtProt AC: NX_Q9H255
    UniProt: Q9H255

  • Chr Location
    11p15.4; chr11:4680171-4697854 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    30 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Targeted inactivation of this gene leads to alterations in olfactory sensory neuron development.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    35
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    734
  • Tissues
    2
  • cDNA Data
    7
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 170639 NCBI Gene Model | MGI Sequence Detail 18751 C57BL/6J ±  kb
    transcript NM_130866 RefSeq | MGI Sequence Detail 3496 C57BL/6  
    polypeptide Q8VBV9 UniProt | EBI | MGI Sequence Detail 320 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 7
      Other 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1918068, MGI:7277427
    References
    more
    • Summaries
      All 59
      Developmental Gene Expression 5
      Gene Ontology 9
      Phenotypes 30
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:350385 Colinas O, et al., Carotid Body Function in Tyrosine Hydroxylase Conditional Olfr78 Knockout Mice. Function (Oxf)22. 2024;(5)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory