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Parvg Gene Detail
Summary
  • Symbol
    Parvg
  • Name
    parvin, gamma
  • Feature Type
    protein coding gene
  • IDs
    MGI:2158329
    NCBI Gene: 64099
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:84208388-84227179 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 39.78 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    679 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2158329
 protein coding gene Chr15:84208227-84227179 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022177
 protein coding gene Chr15:85112377-85131308 (+)
A/J MGP_AJ_G0022136
 protein coding gene Chr15:81965544-81984325 (+)
AKR/J MGP_AKRJ_G0022111
 protein coding gene Chr15:84356781-84375766 (+)
BALB/cJ MGP_BALBcJ_G0022142
 protein coding gene Chr15:82099240-82118146 (+)
C3H/HeJ MGP_C3HHeJ_G0021912
 protein coding gene Chr15:84313637-84335436 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022587
 protein coding gene Chr15:88347987-88369148 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020112
 protein coding gene Chr15:78322279-78341429 (+)
CAST/EiJ MGP_CASTEiJ_G0021434
 protein coding gene Chr15:85113490-85132669 (+)
CBA/J MGP_CBAJ_G0021879
 protein coding gene Chr15:91209956-91232446 (+)
DBA/2J MGP_DBA2J_G0022006
 protein coding gene Chr15:81443819-81462988 (+)
FVB/NJ MGP_FVBNJ_G0021985
 protein coding gene Chr15:80496397-80515365 (+)
LP/J MGP_LPJ_G0022077
 protein coding gene Chr15:85262952-85283671 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022005
 protein coding gene Chr15:96031721-96051765 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022602
 protein coding gene Chr15:84373041-84391972 (+)
PWK/PhJ MGP_PWKPhJ_G0021175
 protein coding gene Chr15:81442431-81463916 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021009
 protein coding gene Chr15:84080847-84099887 (+)
WSB/EiJ MGP_WSBEiJ_G0021483
 protein coding gene Chr15:84867865-84889064 (+)



Homology
more
  • Human Ortholog
    PARVG, parvin gamma
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PARVG, parvin gamma
  • Links
    NCBI Gene ID: 64098
    neXtProt AC: NX_Q9HBI0
    UniProt: Q9HBI0

  • Chr Location
    22q13.31; chr22:44172951-44219533 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    23 phenotype references
Homozygous null mice are viable and fertile with a normal life span and normal immune cell development and function.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    854
  • Tissues
    97
  • cDNA Data
    21
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 64099 NCBI Gene Model | MGI Sequence Detail 18792 C57BL/6J ±  kb
transcript NM_001162500 RefSeq | MGI Sequence Detail 2700 C57BL/6  
polypeptide Q9ERD8 UniProt | EBI | MGI Sequence Detail 331 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    Genomic 1
    cDNA 21

    Microarray probesets 4
Other
Accession IDs
less
MGI:2145990
References
more
  • Summaries
    All 48
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 4
    Phenotypes 23
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:327276 Thievessen I, et al., The focal adhesion protein beta-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load. Curr Biol. 2022 Jul 25;32(14):3033-3047.e9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory