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Hdac10 Gene Detail
Summary
  • Symbol
    Hdac10
  • Name
    histone deacetylase 10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2158340
    NCBI Gene: 170787
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:89007510-89012903 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 44.64 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    140 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2158340
 protein coding gene Chr15:89007506-89012903 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022218
 protein coding gene Chr15:90295348-90301850 (-)
A/J MGP_AJ_G0022177
 protein coding gene Chr15:86845520-86850910 (-)
AKR/J MGP_AKRJ_G0022152
 protein coding gene Chr15:89413023-89418413 (-)
BALB/cJ MGP_BALBcJ_G0022183
 protein coding gene Chr15:86944923-86950537 (-)
C3H/HeJ MGP_C3HHeJ_G0021953
 protein coding gene Chr15:89399367-89404763 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022628
 protein coding gene Chr15:93577668-93583108 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020153
 protein coding gene Chr15:83069725-83075304 (-)
CAST/EiJ MGP_CASTEiJ_G0021475
 protein coding gene Chr15:90179491-90184893 (-)
CBA/J MGP_CBAJ_G0021920
 protein coding gene Chr15:96739867-96745268 (-)
DBA/2J MGP_DBA2J_G0022047
 protein coding gene Chr15:86298869-86304263 (-)
FVB/NJ MGP_FVBNJ_G0022026
 protein coding gene Chr15:85364021-85369419 (-)
LP/J MGP_LPJ_G0022118
 protein coding gene Chr15:90456574-90461980 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022046
 protein coding gene Chr15:101162222-101167758 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022643
 protein coding gene Chr15:89447876-89453274 (-)
PWK/PhJ MGP_PWKPhJ_G0021216
 protein coding gene Chr15:86342922-86348463 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021050
 protein coding gene Chr15:89179264-89184692 (-)
WSB/EiJ MGP_WSBEiJ_G0021524
 protein coding gene Chr15:89932218-89937608 (-)



Homology
more
  • Human Ortholog
    HDAC10, histone deacetylase 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HDAC10, histone deacetylase 10
  • Synonyms
    HD10
  • Links
    NCBI Gene ID: 83933
    neXtProt AC: NX_Q969S8
    UniProt: Q969S8

  • Chr Location
    22q13.33; chr22:50245183-50251405 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    33 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    931
  • Tissues
    86
  • cDNA Data
    46
  • Literature Summary
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000062906 Ensembl Gene Model | MGI Sequence Detail 5394 C57BL/6J ±  kb
    transcript ENSMUST00000082197 Ensembl | MGI Sequence Detail 2412 Not Applicable  
    polypeptide ENSMUSP00000080832 Ensembl | MGI Sequence Detail 666 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 49
      cDNA 47
      Primer pair 2

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2146231
    References
    more
    • Summaries
      All 73
      Developmental Gene Expression 10
      Diseases 1
      Gene Ontology 9
      Phenotypes 33
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:354578 Xiang Y, et al., Myeloid-specific Hdac10 deletion protects against LPS-induced acute lung injury via P62 acetylation at lysine 165. Respir Res. 2024 Jul 2;25(1):263
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory