Gene | Genome Location (GRCm39) | Reference | QTL Note |
Slc11a1 | Chr1:74414354-74425221 (+) | J:107559 | Congenic mouse strains within the Idd5.2 (MGI: Idd5b) region of mouse Chromosome 1 were utilized to suggest that solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (Slc11a1) is a likely candidate for Idd5.2. Using RNAi (RNA interference) the authors showed that a knockdown of Slc11a1 (allele Nramp1) had a detectable effect on diabetes incidence conferred within the Idd5.2 region. |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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