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Cyp4f13 Gene Detail
Summary
  • Symbol
    Cyp4f13
  • Name
    cytochrome P450, family 4, subfamily f, polypeptide 13
  • Synonyms
    0610030I10Rik, leukotriene B4 omega hydroxylase, P450 CYP4F13
  • Feature Type
    protein coding gene
  • IDs
    MGI:2158641
    NCBI Gene: 170716
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:33143662-33166376 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 17.98 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1001 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2158641
 protein coding gene Chr17:33143662-33166389 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023516
 protein coding gene Chr17:32816499-32839875 (-)
A/J MGP_AJ_G0023474
 protein coding gene Chr17:31723763-31748436 (-)
AKR/J MGP_AKRJ_G0023440
 protein coding gene Chr17:32037027-32059385 (-)
BALB/cJ MGP_BALBcJ_G0023479
 protein coding gene Chr17:31821691-31844353 (-)
C3H/HeJ MGP_C3HHeJ_G0023241
 protein coding gene Chr17:32432566-32454995 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023922
 protein coding gene Chr17:33938858-33961336 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021396
 protein coding gene Chr17:28990108-29012535 (-)
CAST/EiJ MGP_CASTEiJ_G0022742
 protein coding gene Chr17:32539457-32563810 (-)
CBA/J MGP_CBAJ_G0023215
 protein coding gene Chr17:35443138-35467596 (-)
DBA/2J MGP_DBA2J_G0023345
 protein coding gene Chr17:31108715-31131646 (-)
FVB/NJ MGP_FVBNJ_G0023315
 protein coding gene Chr17:30921743-30944502 (-)
LP/J MGP_LPJ_G0023424
 protein coding gene Chr17:33036249-33059935 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023334
 protein coding gene Chr17:34433468-34457396 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023964
 protein coding gene Chr17:32402070-32425685 (-)
PWK/PhJ MGP_PWKPhJ_G0022489
 protein coding gene Chr17:30031653-30055162 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022309
 protein coding gene Chr17:30378522-30404375 (-)
WSB/EiJ MGP_WSBEiJ_G0022803
 protein coding gene Chr17:32415887-32440274 (-)



Homology
more
  • Human Ortholog
    CYP4F3, cytochrome P450 family 4 subfamily F member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP4F3, cytochrome P450 family 4 subfamily F member 3
  • Synonyms
    CPF3, CYP4F, CYPIVF3, LTB4H
  • Links
    NCBI Gene ID: 4051
    neXtProt AC: NX_Q08477
    UniProt: Q08477

  • Chr Location
    19p13.12; chr19:15640897-15662825 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CYP4F8 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from multigenic genotypes
    6 phenotype references
Mice homozygous for a null allele exhibit susceptibility to atherosclerosis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    813
  • Tissues
    107
  • cDNA Data
    55
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024055 Ensembl Gene Model | MGI Sequence Detail 22715 C57BL/6J ±  kb
transcript ENSMUST00000075253 Ensembl | MGI Sequence Detail 1752 Not Applicable  
polypeptide ENSMUSP00000074733 Ensembl | MGI Sequence Detail 523 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 56
    cDNA 55
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1915640
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:289999 Han J, et al., Confirmation of Ath26 locus on chromosome 17 and identification of Cyp4f13 as an atherosclerosis modifying gene. Atherosclerosis. 2019 Jul;286:71-78
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory