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Ntng2 Gene Detail
Summary
  • Symbol
    Ntng2
  • Name
    netrin G2
  • Synonyms
    2610016D08Rik, Lmnt2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2159341
    NCBI Gene: 171171
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr2:29084738-29138111 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 19.57 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1378 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2159341
 protein coding gene Chr2:29084553-29143017 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025538
 protein coding gene Chr2:27314333-27377203 (-)
A/J MGP_AJ_G0025515
 protein coding gene Chr2:26265751-26330064 (-)
AKR/J MGP_AKRJ_G0025485
 protein coding gene Chr2:27143000-27202938 (-)
BALB/cJ MGP_BALBcJ_G0025511
 protein coding gene Chr2:26393158-26453414 (-)
C3H/HeJ MGP_C3HHeJ_G0025272
 protein coding gene Chr2:27062022-27125462 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025955
 protein coding gene Chr2:28213274-28276772 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023365
 protein coding gene Chr2:25070974-25128672 (-)
CAST/EiJ MGP_CASTEiJ_G0024735
 protein coding gene Chr2:26963680-27025059 (-)
CBA/J MGP_CBAJ_G0025250
 protein coding gene Chr2:29174746-29247952 (-)
DBA/2J MGP_DBA2J_G0025383
 protein coding gene Chr2:26060634-26118780 (-)
FVB/NJ MGP_FVBNJ_G0025345
 protein coding gene Chr2:25865164-25923624 (-)
LP/J MGP_LPJ_G0025469
 protein coding gene Chr2:27248878-27319467 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025376
 protein coding gene Chr2:29159359-29220026 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026014
 protein coding gene Chr2:27051499-27114956 (-)
PWK/PhJ MGP_PWKPhJ_G0024482
 protein coding gene Chr2:25875549-25936534 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024282
 protein coding gene Chr2:27154984-27218308 (-)
WSB/EiJ MGP_WSBEiJ_G0024804
 protein coding gene Chr2:27182206-27250033 (-)



Homology
more
  • Human Ortholog
    NTNG2, netrin G2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NTNG2, netrin G2
  • Synonyms
    bA479K20.1, LHLL9381, Lmnt2, NEDBASH, NetrinG2, NTNG1
  • Links
    NCBI Gene ID: 84628
    neXtProt AC: NX_Q96CW9
    UniProt: Q96CW9

  • Chr Location
    9q34.13; chr9:132161689-132244526 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit an absence of startle reflex and abnormal ABR amplitude.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    925
  • Tissues
    91
  • cDNA Data
    10
  • Literature Summary
    18
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 171171 NCBI Gene Model | MGI Sequence Detail 53374 C57BL/6J ±  kb
transcript NM_133501 RefSeq | MGI Sequence Detail 2672 C57BL/6  
polypeptide Q8R4F1 UniProt | EBI | MGI Sequence Detail 589 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1919701
References
more
  • Summaries
    All 52
    Developmental Gene Expression 18
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:354180 Xu M, et al., ISL1 and POU4F1 Directly Interact to Regulate the Differentiation and Survival of Inner Ear Sensory Neurons. J Neurosci. 2024 Feb 21;44(8)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory