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Ovca2 Gene Detail
Summary
  • Symbol
    Ovca2
  • Name
    candidate tumor suppressor in ovarian cancer 2
  • Synonyms
    9030414M07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2179725
    NCBI Gene: 246257
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:75066769-75069634 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 45.76 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    146 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2179725
 protein coding gene Chr11:75066768-75069661 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018705
 protein coding gene Chr11:75907542-75910435 (-)
A/J MGP_AJ_G0018671
 protein coding gene Chr11:73088481-73091374 (-)
AKR/J MGP_AKRJ_G0018641
 protein coding gene Chr11:75303411-75306304 (-)
BALB/cJ MGP_BALBcJ_G0018645
 protein coding gene Chr11:73459180-73462073 (-)
C3H/HeJ MGP_C3HHeJ_G0018458
 protein coding gene Chr11:75317256-75320149 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019096
 protein coding gene Chr11:78283846-78286739 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016731
 protein coding gene Chr11:70105161-70108136 (-)
CAST/EiJ MGP_CASTEiJ_G0018012
 protein coding gene Chr11:75704788-75707694 (-)
CBA/J MGP_CBAJ_G0018428
 protein coding gene Chr11:81719562-81722455 (-)
DBA/2J MGP_DBA2J_G0018537
 protein coding gene Chr11:72694533-72697426 (-)
FVB/NJ MGP_FVBNJ_G0018527
 protein coding gene Chr11:72257133-72260026 (-)
LP/J MGP_LPJ_G0018608
 protein coding gene Chr11:76501710-76504603 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018553
 protein coding gene Chr11:82305859-82308752 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019136
 protein coding gene Chr11:75489077-75491970 (-)
PWK/PhJ MGP_PWKPhJ_G0017783
 protein coding gene Chr11:73390788-73393688 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017574
 protein coding gene Chr11:75060116-75063029 (-)
WSB/EiJ MGP_WSBEiJ_G0018065
 protein coding gene Chr11:75308054-75310947 (-)



Homology
more
  • Human Ortholog
    OVCA2, OVCA2 serine hydrolase domain containing
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OVCA2, OVCA2 serine hydrolase domain containing
  • Links
    NCBI Gene ID: 124641
    neXtProt AC: NX_Q8WZ82
    UniProt: Q8WZ82

  • Chr Location
    17p13.3; chr17:2042022-2043425 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Ovca2
  • Find Mice (IMSR)
    5 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 246257 NCBI Gene Model | MGI Sequence Detail 2866 C57BL/6J ±  kb
transcript NM_027136 RefSeq | MGI Sequence Detail 2642 C57BL/6  
polypeptide Q9D7E3 UniProt | EBI | MGI Sequence Detail 225 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    Genomic 2
    cDNA 7

    Microarray probesets 2
Other
Accession IDs
less
MGI:2447859
References
more
  • Summaries
    All 31
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory