Tg(Mx1-cre)29-4Her
Transgene Detail

Summary

• Symbol: Tg(Mx1-cre)29-4Her
• Name: transgene insertion 29-4, Joachim Herz
• MGI ID: MGI:2180899
• Synonyms: MX1 cre, MX1Cre
• Transgene: Tg(Mx1-cre)29-4Her Location: unknown
• Alliance: Tg(Mx1-cre)29-4Her page

Transgene origin

• Strain of Origin: SJL x C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: interferon or polyinosinic-polycytidylic acid
• Mutation: Insertion
• Tg(Mx1-cre)29-4Her expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Mx1

• Mutation details: This transgene expresses Cre recombinase under the control of an interferon-inducible promoter. This promoter can be induced in the liver, but not the brain. Approximately 10 copies of the transgene were integrated into this line. (J:67929)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Mx1 (species not specified) Summary of all recombinase alleles driven by Mx1. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:67929 Rohlmann A, et al., Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants. J Clin Invest. 1998 Feb 1;101(3):689-95
• All: 33 reference(s)