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Aard Gene Detail
Summary
  • Symbol
    Aard
  • Name
    alanine and arginine rich domain containing protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:2181621
    NCBI Gene: 239435
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:51903503-51909118 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 19.55 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    257 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2181621
 protein coding gene Chr15:51903503-51909118 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021840
 protein coding gene Chr15:51002815-51008430 (+)
A/J MGP_AJ_G0021800
 protein coding gene Chr15:48967902-48973517 (+)
AKR/J MGP_AKRJ_G0021781
 protein coding gene Chr15:50356215-50361830 (+)
BALB/cJ MGP_BALBcJ_G0021807
 protein coding gene Chr15:49231254-49236869 (+)
C3H/HeJ MGP_C3HHeJ_G0021581
 protein coding gene Chr15:50474623-50480238 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022246
 protein coding gene Chr15:52996640-53002455 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019783
 protein coding gene Chr15:46037487-46043120 (+)
CAST/EiJ MGP_CASTEiJ_G0021098
 protein coding gene Chr15:51029206-51034817 (+)
CBA/J MGP_CBAJ_G0021550
 protein coding gene Chr15:54918230-54923845 (+)
DBA/2J MGP_DBA2J_G0021674
 protein coding gene Chr15:48846107-48851722 (+)
FVB/NJ MGP_FVBNJ_G0021652
 protein coding gene Chr15:48056571-48070165 (+)
LP/J MGP_LPJ_G0021744
 protein coding gene Chr15:50801449-50807064 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021676
 protein coding gene Chr15:59909025-59916065 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022269
 protein coding gene Chr15:50703945-50709560 (+)
PWK/PhJ MGP_PWKPhJ_G0020843
 protein coding gene Chr15:48953501-48960168 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020680
 protein coding gene Chr15:50441645-50447265 (+)
WSB/EiJ MGP_WSBEiJ_G0021153
 protein coding gene Chr15:50696448-50702062 (+)



Homology
more
  • Human Ortholog
    AARD, alanine and arginine rich domain containing protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AARD, alanine and arginine rich domain containing protein
  • Synonyms
    C8orf85
  • Links
    NCBI Gene ID: 441376
    neXtProt AC: NX_Q4LEZ3
    UniProt: Q4LEZ3

  • Chr Location
    8q24.11; chr8:116938207-116944487 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotype references
  • All Mutations and Alleles
    40
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Gene trapped
    33
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    3 involving Aard
  • Find Mice (IMSR)
    11 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1002
  • Tissues
    153
  • cDNA Data
    11
  • Literature Summary
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 239435 NCBI Gene Model | MGI Sequence Detail 5616 C57BL/6J ±  kb
transcript NM_175503 RefSeq | MGI Sequence Detail 1360 C57BL/6  
polypeptide Q811W1 UniProt | EBI | MGI Sequence Detail 167 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    Genomic 1
    cDNA 11
    Primer pair 3

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146173
References
more
  • Summaries
    All 51
    Developmental Gene Expression 11
    Diseases 1
    Gene Ontology 1
    Phenotypes 21
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory