Map7d1 MGI Mouse Gene Detail - MGI:2384297

Symbol

Map7d1
Name

MAP7 domain containing 1
Synonyms

MGC:27585, MGC:28498, Mtap7d1, Parcc1, Rprc1

Feature Type

protein coding gene
IDs

MGI:2384297
NCBI Gene: 245877
Alliance

gene page
Transcription Start Sites

11 TSS

Sequence Map

Chr4:126125960-126150112 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 4, 60.16 cM
Mapping Data

2 experiments

SNPs within 2kb

589 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2384297	protein coding gene	Chr4:126125960-126150136 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0028775	protein coding gene	Chr4:127901172-127926951 (-)
A/J	MGP_AJ_G0028734	protein coding gene	Chr4:122867111-122892372 (-)
AKR/J	MGP_AKRJ_G0028687	protein coding gene	Chr4:126247110-126271276 (-)
BALB/cJ	MGP_BALBcJ_G0028757	protein coding gene	Chr4:123443972-123469598 (-)
C3H/HeJ	MGP_C3HHeJ_G0028471	protein coding gene	Chr4:126309898-126335011 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0029199	protein coding gene	Chr4:132789228-132814833 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0026472	protein coding gene	Chr4:116012743-116037220 (-)
CAST/EiJ	MGP_CASTEiJ_G0027904	protein coding gene	Chr4:124413014-124441472 (-)
CBA/J	MGP_CBAJ_G0028437	protein coding gene	Chr4:135993550-136021728 (-)
DBA/2J	MGP_DBA2J_G0028586	protein coding gene	Chr4:123322147-123346533 (-)
FVB/NJ	MGP_FVBNJ_G0028553	protein coding gene	Chr4:121974767-122000227 (-)
LP/J	MGP_LPJ_G0028687	protein coding gene	Chr4:128186919-128213824 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0028579	protein coding gene	Chr4:141020250-141050016 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0029237	protein coding gene	Chr4:126597633-126622831 (-)
PWK/PhJ	MGP_PWKPhJ_G0027625	protein coding gene	Chr4:119800505-119826816 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0027451	protein coding gene	Chr4:122422581-122446865 (-)
WSB/EiJ	MGP_WSBEiJ_G0027984	protein coding gene	Chr4:126696242-126723842 (-)

Human Ortholog

MAP7D1, MAP7 domain containing 1

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MAP7D1, MAP7 domain containing 1
Synonyms

PARCC1, RPRC1
Links

HGNC:25514

NCBI Gene ID: 55700

neXtProt AC: NX_Q3KQU3

UniProt: Q3KQU3
Chr Location

1p34.3; chr1:36155579-36180849 (+) GRCh38

MGI Vertebrate Homology

Map7d1 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: MAP7D1
Gene Tree

Map7d1

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Phenotype Summary

3 phenotypes from 1 allele in 1 genetic background
14 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

22
Chemically induced (other)

2
Endonuclease-mediated

3
Gene trapped

14
Radiation induced

1
Targeted

2
Genomic Mutations

4 involving Map7d1
Incidental Mutations

APF , CvDC
Find Mice (IMSR)

46 strains or lines available

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All GO Annotations

5
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

736
Tissues

5
cDNA Data

136
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase map7d1

ZFIN map7d1a

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All Sequences

77
RefSeq

16
UniProt

4
CCDS

CCDS18646.1, CCDS51302.1, CCDS84793.1

Ensembl

ENSMUSG00000028849 (Evidence)
NCBI Gene

245877

			Length	Strain/Species	Flank
genomic	245877	NCBI Gene Model \| MGI Sequence Detail	24153	C57BL/6J	± kb
transcript	NM_144941	RefSeq \| MGI Sequence Detail	3402	C57BL/6
polypeptide	A2AJI0	UniProt \| EBI \| MGI Sequence Detail	846	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000031125 MAP7 domain-containing protein 1

(term hierarchy)
InterPro Domains

IPR051483 Microtubule-associated protein 7 domain-containing protein

IPR008604 Microtubule-associated protein 7 family
GlyGen

A2AJI0 2 sites, 1 O-linked glycan (2 sites)

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All nucleic 136

cDNA 136

Microarray probesets 5

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MGI:2140518

Summaries

All 38

Developmental Gene Expression 1

Gene Ontology 4

Phenotypes 14
Earliest

J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Map7d1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr43370	Chr4:126150019-126150163 (-)	21 bp
Tssr43369	Chr4:126149866-126149894 (-)	232 bp
Tssr43368	Chr4:126143290-126143295 (-)	6,819 bp
Tssr43367	Chr4:126136085-126136123 (-)	14,008 bp
Tssr43366	Chr4:126136051-126136079 (-)	14,047 bp
Tssr43365	Chr4:126135971-126135986 (-)	14,133 bp
Tssr43364	Chr4:126135908-126135919 (-)	14,198 bp
Tssr43363	Chr4:126135874-126135889 (-)	14,230 bp
Tssr43362	Chr4:126135849-126135870 (-)	14,252 bp
Tssr43361	Chr4:126131598-126131638 (-)	18,494 bp
Tssr43360	Chr4:126130377-126130425 (-)	19,711 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24