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Lrrc3b Gene Detail
Summary
  • Symbol
    Lrrc3b
  • Name
    leucine rich repeat containing 3B
  • Synonyms
    LRP15
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384996
    NCBI Gene: 218763
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:7030776-7112248 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 7.08 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2674 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384996
 protein coding gene Chr14:7030776-7112248 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021013
 protein coding gene Chr14:7962039-8047976 (-)
A/J MGP_AJ_G0020961
 protein coding gene Chr14:7723263-7807913 (-)
AKR/J MGP_AKRJ_G0020938
 protein coding gene Chr14:7910993-7993905 (-)
BALB/cJ MGP_BALBcJ_G0020964
 protein coding gene Chr14:7756680-7838405 (-)
C3H/HeJ MGP_C3HHeJ_G0020748
 protein coding gene Chr14:8026547-8109039 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021397
 protein coding gene Chr14:8188369-8290216 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018966
 protein coding gene Chr14:8358107-8438686 (-)
CAST/EiJ MGP_CASTEiJ_G0020271
 protein coding gene Chr14:7918521-7998693 (-)
CBA/J MGP_CBAJ_G0020714
 protein coding gene Chr14:8535837-8627807 (-)
DBA/2J MGP_DBA2J_G0020838
 protein coding gene Chr14:7660153-7741941 (-)
FVB/NJ MGP_FVBNJ_G0020820
 protein coding gene Chr14:7545839-7628626 (-)
LP/J MGP_LPJ_G0020913
 protein coding gene Chr14:7992529-8079215 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020846
 protein coding gene Chr14:8488055-8568711 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021430
 protein coding gene Chr14:7798303-7885480 (-)
PWK/PhJ MGP_PWKPhJ_G0020022
 protein coding gene Chr14:7694097-7777499 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019842
 protein coding gene Chr14:8001199-8082540 (-)
WSB/EiJ MGP_WSBEiJ_G0020328
 protein coding gene Chr14:7878878-7966037 (-)



Homology
more
  • Human Ortholog
    LRRC3B, leucine rich repeat containing 3B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC3B, leucine rich repeat containing 3B
  • Synonyms
    LRP15
  • Links
    NCBI Gene ID: 116135
    neXtProt AC: NX_Q96PB8
    UniProt: Q96PB8

  • Chr Location
    3p24.1; chr3:26622772-26717537 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Mice homozygous for a knock-out allele exhibit normal olfactory epithelium and bulb.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 218763 NCBI Gene Model | MGI Sequence Detail 81473 C57BL/6J ±  kb
transcript NM_001425741 RefSeq | MGI Sequence Detail 2231 C57BL/6  
polypeptide Q8VCH9 UniProt | EBI | MGI Sequence Detail 259 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000031567 leucine-rich repeat-containing protein 3B
    (term hierarchy)
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR050541 Leucine-rich repeat and transmembrane domain-containing protein
    IPR032675 Leucine-rich repeat domain superfamily
    IPR000372 Leucine-rich repeat N-terminal domain
    IPR003591 Leucine-rich repeat, typical subtype
  • GlyGen
    Q8VCH9 2 sites, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:144660 Yoshida Y, et al., PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord. Neuron. 2006 Dec 7;52(5):775-88
  • Latest
    J:299344 Fischl AM, et al., Activity-dependent genes in mouse olfactory sensory neurons. Chem Senses. 2014 Jun;39(5):439-49
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory