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Ggact Gene Detail
Summary
  • Symbol
    Ggact
  • Name
    gamma-glutamylamine cyclotransferase
  • Synonyms
    A2ld1, MGC:7867
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385008
    NCBI Gene: 223267
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:123128272-123151173 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 66.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    390 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385008
 protein coding gene Chr14:123053635-123151173 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021675
 protein coding gene Chr14:120732580-120831716 (-)
A/J MGP_AJ_G0021635
 protein coding gene Chr14:116059808-116156890 (-)
AKR/J MGP_AKRJ_G0021611
 protein coding gene Chr14:119803411-119905398 (-)
BALB/cJ MGP_BALBcJ_G0021641
 protein coding gene Chr14:116607281-116703504 (-)
C3H/HeJ MGP_C3HHeJ_G0021418
 protein coding gene Chr14:119705273-119803975 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022081
 protein coding gene Chr14:125380062-125482341 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019619
 protein coding gene Chr14:111874174-111971313 (-)
CAST/EiJ MGP_CASTEiJ_G0020934
 protein coding gene Chr14:117597718-117696335 (-)
CBA/J MGP_CBAJ_G0021387
 protein coding gene Chr14:130132411-130245406 (-)
DBA/2J MGP_DBA2J_G0021510
 protein coding gene Chr14:115909663-116006994 (-)
FVB/NJ MGP_FVBNJ_G0021488
 protein coding gene Chr14:114266180-114361769 (-)
LP/J MGP_LPJ_G0021578
 protein coding gene Chr14:121637067-121737890 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021515
 protein coding gene Chr14:135111489-135217419 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022104
 protein coding gene Chr14:119389175-119490181 (-)
PWK/PhJ MGP_PWKPhJ_G0020678
 protein coding gene Chr14:112959694-113057712 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020516
 protein coding gene Chr14:115572706-115678077 (-)
WSB/EiJ MGP_WSBEiJ_G0020990
 protein coding gene Chr14:120077834-120177516 (-)



Homology
more
  • Human Ortholog
    GGACT, gamma-glutamylamine cyclotransferase
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GGACT, gamma-glutamylamine cyclotransferase
  • Synonyms
    A2LD1
  • Links
    NCBI Gene ID: 87769
    neXtProt AC: NX_Q9BVM4
    UniProt: Q9BVM4

  • Chr Location
    13q32.3; chr13:100530164-100589528 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 223267 NCBI Gene Model | MGI Sequence Detail 22902 C57BL/6J ±  kb
transcript NM_001425808 RefSeq | MGI Sequence Detail 1523 C57BL/6  
polypeptide Q923B0 UniProt | EBI | MGI Sequence Detail 149 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory