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Nrbp2 Gene Detail
Summary
  • Symbol
    Nrbp2
  • Name
    nuclear receptor binding protein 2
  • Synonyms
    MGC:12117, MGC:18994
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385017
    NCBI Gene: 223649
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:75957367-75963476 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 35.35 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    170 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385017
 protein coding gene Chr15:75957364-75963539 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021975
 protein coding gene Chr15:76137647-76143553 (-)
A/J MGP_AJ_G0021933
 protein coding gene Chr15:73369512-73375492 (-)
AKR/J MGP_AKRJ_G0021916
 protein coding gene Chr15:75357694-75362111 (-)
BALB/cJ MGP_BALBcJ_G0021942
 protein coding gene Chr15:73388217-73394199 (-)
C3H/HeJ MGP_C3HHeJ_G0021714
 protein coding gene Chr15:75412573-75416990 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022382
 protein coding gene Chr15:78980670-78985087 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019911
 protein coding gene Chr15:70037802-70042208 (-)
CAST/EiJ MGP_CASTEiJ_G0021233
 protein coding gene Chr15:76198786-76203196 (-)
CBA/J MGP_CBAJ_G0021681
 protein coding gene Chr15:81493014-81498920 (-)
DBA/2J MGP_DBA2J_G0021806
 protein coding gene Chr15:72898828-72904810 (-)
FVB/NJ MGP_FVBNJ_G0021787
 protein coding gene Chr15:71952622-71957039 (-)
LP/J MGP_LPJ_G0021877
 protein coding gene Chr15:76231887-76236304 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021811
 protein coding gene Chr15:86794770-86800756 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022402
 protein coding gene Chr15:75606211-75610628 (-)
PWK/PhJ MGP_PWKPhJ_G0020974
 protein coding gene Chr15:73048584-73053001 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020813
 protein coding gene Chr15:75325068-75330959 (-)
WSB/EiJ MGP_WSBEiJ_G0021285
 protein coding gene Chr15:75688656-75694564 (-)



Homology
more
  • Human Ortholog
    NRBP2, nuclear receptor binding protein 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NRBP2, nuclear receptor binding protein 2
  • Synonyms
    pp9320, TRG16
  • Links
    NCBI Gene ID: 340371
    neXtProt AC: NX_Q9NSY0
    UniProt: Q9NSY0

  • Chr Location
    8q24.3; chr8:143829776-143840973 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    32 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    749
  • Tissues
    30
  • cDNA Data
    61
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075590 Ensembl Gene Model | MGI Sequence Detail 6110 C57BL/6J ±  kb
transcript ENSMUST00000228366 Ensembl | MGI Sequence Detail 3192 Not Applicable  
polypeptide ENSMUSP00000154287 Ensembl | MGI Sequence Detail 499 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000011419 nuclear receptor-binding protein 2
    (term hierarchy)
  • InterPro Domains
    IPR042697 Nuclear receptor-binding protein 2, pseudokinase domain
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain superfamily
    IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
    IPR050588 With No Lysine (K) Ser/Thr Protein Kinase
Molecular
Reagents
less
  • All nucleic 61
    cDNA 61

    Microarray probesets 4
References
more
  • Summaries
    All 60
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 5
    Phenotypes 32
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory