Csrnp2 MGI Mouse Gene Detail - MGI:2386852 - cysteine-serine-rich nuclear protein 2

Symbol

Csrnp2
Name

cysteine-serine-rich nuclear protein 2
Synonyms

CSRNP-2, MGC:28165

Feature Type

protein coding gene
IDs

MGI:2386852
NCBI Gene: 207785
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr15:100377451-100393120 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 15, 56.32 cM
Mapping Data

1 experiment

SNPs within 2kb

348 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2386852	protein coding gene	Chr15:100377451-100393369 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0022353	protein coding gene	Chr15:102442638-102458324 (-)
A/J	MGP_AJ_G0022315	protein coding gene	Chr15:98404666-98420321 (-)
AKR/J	MGP_AKRJ_G0022291	protein coding gene	Chr15:101416515-101432175 (-)
BALB/cJ	MGP_BALBcJ_G0022319	protein coding gene	Chr15:98525198-98540863 (-)
C3H/HeJ	MGP_C3HHeJ_G0022089	protein coding gene	Chr15:101491529-101514179 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0022767	protein coding gene	Chr15:106296894-106315165 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020292	protein coding gene	Chr15:94177414-94192922 (-)
CAST/EiJ	MGP_CASTEiJ_G0021614	protein coding gene	Chr15:102357758-102374753 (-)
CBA/J	MGP_CBAJ_G0022058	protein coding gene	Chr15:109934631-109950296 (-)
DBA/2J	MGP_DBA2J_G0022185	protein coding gene	Chr15:97773264-97788855 (-)
FVB/NJ	MGP_FVBNJ_G0022164	protein coding gene	Chr15:96785171-96800814 (-)
LP/J	MGP_LPJ_G0022256	protein coding gene	Chr15:102614331-102630017 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0022185	protein coding gene	Chr15:113654830-113670611 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0022781	protein coding gene	Chr15:101423471-101439156 (-)
PWK/PhJ	MGP_PWKPhJ_G0021353	protein coding gene	Chr15:97899575-97915309 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0021185	protein coding gene	Chr15:101320239-101335912 (-)
WSB/EiJ	MGP_WSBEiJ_G0021664	protein coding gene	Chr15:102050393-102066079 (-)

Human Ortholog

CSRNP2, cysteine and serine rich nuclear protein 2

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CSRNP2, cysteine and serine rich nuclear protein 2
Synonyms

C12orf2, C12orf22, FAM130A1, PPP1R72, TAIP-12
Links

HGNC:16006

NCBI Gene ID: 81566

neXtProt AC: NX_Q9H175

UniProt: Q9H175
Chr Location

12q13.12; chr12:51061205-51083664 (-) GRCh38

MGI Vertebrate Homology

Csrnp2 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: CSRNP2
Gene Tree

Csrnp2

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References

1 with disease annotations

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Phenotype Summary

3 phenotypes from 1 allele in 1 genetic background
5 phenotypes from multigenic genotypes
27 phenotype references

All Mutations and Alleles

14
Chemically induced (other)

1
Endonuclease-mediated

2
Gene trapped

6
Radiation induced

2
Targeted

3
Genomic Mutations

3 involving Csrnp2
Incidental Mutations

APF
Find Mice (IMSR)

19 strains or lines available

Mice homozygous for a knock-out allele are viable, fertile and healthy and display normal development, hematopoiesis and T cell function.

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All GO Annotations

13
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

721
Tissues

13
cDNA Data

49
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase csrnp2

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All Sequences

40
RefSeq

4
UniProt

1
CCDS

CCDS27839.1

Ensembl

ENSMUSG00000044636 (Evidence)
NCBI Gene

207785

			Length	Strain/Species	Flank
genomic	207785	NCBI Gene Model \| MGI Sequence Detail	15670	C57BL/6J	± kb
transcript	NM_153407	RefSeq \| MGI Sequence Detail	4126	C57BL/6
polypeptide	Q8BGQ2	UniProt \| EBI \| MGI Sequence Detail	534	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000005956 cysteine/serine-rich nuclear protein 2

(term hierarchy)
InterPro Domains

IPR023260 Cysteine/serine-rich nuclear protein family

IPR031972 Cysteine/serine-rich nuclear protein, N-terminal domain

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All nucleic 50

cDNA 50

Microarray probesets 2

Summaries

All 50

Developmental Gene Expression 2

Diseases 1

Gene Ontology 5

Phenotypes 27
Earliest

J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
Latest

J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27

TSS for Csrnp2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr136433	Chr15:100393132-100393148 (-)	-20 bp
Tssr136432	Chr15:100392936-100392938 (-)	183 bp
Tssr136431	Chr15:100389733-100389734 (-)	3,386 bp
Tssr136430	Chr15:100384487-100384511 (-)	8,621 bp
Tssr136429	Chr15:100378464-100378469 (-)	14,653 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24