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Qsox2 Gene Detail
Summary
  • Symbol
    Qsox2
  • Name
    quiescin Q6 sulfhydryl oxidase 2
  • Synonyms
    Qscn6l1, QSOX2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387194
    NCBI Gene: 227638
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:26099136-26127411 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 18.45 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    678 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387194
 protein coding gene Chr2:26098649-26127537 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025479
 protein coding gene Chr2:24160830-24190342 (-)
A/J MGP_AJ_G0025456
 protein coding gene Chr2:23226634-23254981 (-)
AKR/J MGP_AKRJ_G0025426
 protein coding gene Chr2:23981949-24012322 (-)
BALB/cJ MGP_BALBcJ_G0025452
 protein coding gene Chr2:23337771-23366300 (-)
C3H/HeJ MGP_C3HHeJ_G0025213
 protein coding gene Chr2:23941859-23970787 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025896
 protein coding gene Chr2:24932902-24965411 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023307
 protein coding gene Chr2:22109071-22137298 (-)
CAST/EiJ MGP_CASTEiJ_G0024676
 protein coding gene Chr2:23811986-23842032 (-)
CBA/J MGP_CBAJ_G0025191
 protein coding gene Chr2:25774472-25805762 (-)
DBA/2J MGP_DBA2J_G0025324
 protein coding gene Chr2:23052476-23080876 (-)
FVB/NJ MGP_FVBNJ_G0025286
 protein coding gene Chr2:22801070-22830658 (-)
LP/J MGP_LPJ_G0025410
 protein coding gene Chr2:24096235-24126138 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025317
 protein coding gene Chr2:25936819-25966201 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025955
 protein coding gene Chr2:23944408-23972660 (-)
PWK/PhJ MGP_PWKPhJ_G0024424
 protein coding gene Chr2:22851758-22879868 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024224
 protein coding gene Chr2:24073063-24101238 (-)
WSB/EiJ MGP_WSBEiJ_G0024745
 protein coding gene Chr2:24049844-24078233 (-)



Homology
more
  • Human Ortholog
    QSOX2, quiescin sulfhydryl oxidase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    QSOX2, quiescin sulfhydryl oxidase 2
  • Synonyms
    QSCN6L1, SOXN
  • Links
    NCBI Gene ID: 169714
    neXtProt AC: NX_Q6ZRP7
    UniProt: Q6ZRP7

  • Chr Location
    9q34.3; chr9:136206333-136245812 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    36
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 227638 NCBI Gene Model | MGI Sequence Detail 28276 C57BL/6J ±  kb
transcript NM_001302956 RefSeq | MGI Sequence Detail 3914 C57BL/6  
polypeptide Q3TMX7 UniProt | EBI | MGI Sequence Detail 692 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 36
    cDNA 36

    Microarray probesets 2
References
more
  • Summaries
    All 34
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:78854 Thorpe C, et al., Sulfhydryl oxidases: emerging catalysts of protein disulfide bond formation in eukaryotes. Arch Biochem Biophys. 2002 Sep 1;405(1):1-12
  • Latest
    J:347242 Chen SY, et al., Cre-LoxP and tamoxifen-induced deletion of ovarian quiescin sulfhydryl oxidase 2 showed disruption of ovulatory activity in mice. J Ovarian Res. 2024 Mar 19;17(1):66
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory