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Trim60 Gene Detail
Summary
  • Symbol
    Trim60
  • Name
    tripartite motif-containing 60
  • Synonyms
    2czf45, Rnf33
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387430
    NCBI Gene: 234329
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:65451959-65471236 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 32.51 cM, cytoband B3.1-3.2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    823 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387430
 protein coding gene Chr8:65451100-65471340 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033647
 protein coding gene Chr8:65021404-65042626 (-)
A/J MGP_AJ_G0033629
 protein coding gene Chr8:62280632-62303388 (-)
AKR/J MGP_AKRJ_G0033554
 protein coding gene Chr8:64049206-64070563 (-)
BALB/cJ MGP_BALBcJ_G0033625
 protein coding gene Chr8:62566236-62586944 (-)
C3H/HeJ MGP_C3HHeJ_G0033335
 protein coding gene Chr8:64788620-64814589 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034142
 protein coding gene Chr8:67449772-67473052 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031089
 protein coding gene Chr8:57546426-57566059 (-)
CAST/EiJ MGP_CASTEiJ_G0032660
 protein coding gene Chr8:64249406-64273776 (-)
CBA/J MGP_CBAJ_G0033313
 protein coding gene Chr8:69953650-69973518 (-)
DBA/2J MGP_DBA2J_G0033467
 protein coding gene Chr8:62098761-62119013 (-)
FVB/NJ MGP_FVBNJ_G0033408
 protein coding gene Chr8:61312751-61335099 (-)
LP/J MGP_LPJ_G0033555
 protein coding gene Chr8:65056167-65076901 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033452
 protein coding gene Chr8:72496386-72518086 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034160
 protein coding gene Chr8:64350292-64374491 (-)
PWK/PhJ MGP_PWKPhJ_G0032369
 protein coding gene Chr8:61431086-61452066 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032205
 protein coding gene Chr8:63337428-63357923 (-)
WSB/EiJ MGP_WSBEiJ_G0032777
 protein coding gene Chr8:64742243-64761965 (-)



Homology
more
  • Human Ortholog
    TRIM60, tripartite motif containing 60
  • Vertebrate Orthologs
    9
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM60, tripartite motif containing 60
  • Synonyms
    RNF129, RNF33
  • Links
    NCBI Gene ID: 166655
    neXtProt AC: NX_Q495X7
    UniProt: Q495X7

  • Chr Location
    4q32.3; chr4:165016458-165041749 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    811
  • Tissues
    78
  • cDNA Data
    11
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053490 Ensembl Gene Model | MGI Sequence Detail 19278 C57BL/6J ±  kb
transcript ENSMUST00000048565 Ensembl | MGI Sequence Detail 2670 Not Applicable  
polypeptide ENSMUSP00000040299 Ensembl | MGI Sequence Detail 466 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:72314 Choo KB, et al., In silico mining of EST databases for novel pre-implantation embryo-specific zinc finger protein genes. Mol Reprod Dev. 2001 Jul;59(3):249-55
  • Latest
    J:207074 Huang CJ, et al., Association of the testis-specific TRIM/RBCC protein RNF33/TRIM60 with the cytoplasmic motor proteins KIF3A and KIF3B. Mol Cell Biochem. 2012 Jan;360(1-2):121-31
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory