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Plppr3 Gene Detail
Summary
  • Symbol
    Plppr3
  • Name
    phospholipid phosphatase related 3
  • Synonyms
    BC005764, Lppr3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2388640
    NCBI Gene: 216152
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:79696309-79710468 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    262 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2388640
protein coding gene Chr10:79696309-79710948 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017464
protein coding gene Chr10:80416713-80429783 (-)
A/J MGP_AJ_G0017442
protein coding gene Chr10:77614983-77629828 (-)
AKR/J MGP_AKRJ_G0017403
protein coding gene Chr10:79728236-79743698 (-)
BALB/cJ MGP_BALBcJ_G0017404
protein coding gene Chr10:77841067-77855909 (-)
C3H/HeJ MGP_C3HHeJ_G0017227
protein coding gene Chr10:79832504-79847602 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017858
protein coding gene Chr10:83190659-83206742 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015546
protein coding gene Chr10:73840653-73856080 (-)
CAST/EiJ MGP_CASTEiJ_G0016794
protein coding gene Chr10:80018173-80034109 (-)
CBA/J MGP_CBAJ_G0017199
protein coding gene Chr10:86416996-86436187 (-)
DBA/2J MGP_DBA2J_G0017305
protein coding gene Chr10:76829869-76844663 (-)
FVB/NJ MGP_FVBNJ_G0017299
protein coding gene Chr10:76008938-76022069 (-)
LP/J MGP_LPJ_G0017376
protein coding gene Chr10:80893146-80910005 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017325
protein coding gene Chr10:88389765-88408914 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017899
protein coding gene Chr10:79712153-79730967 (-)
PWK/PhJ MGP_PWKPhJ_G0016575
protein coding gene Chr10:76691824-76706254 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016364
protein coding gene Chr10:78687988-78702792 (-)
WSB/EiJ MGP_WSBEiJ_G0016854
protein coding gene Chr10:79735743-79751574 (-)



Homology
more
  • Human Ortholog
    PLPPR3, phospholipid phosphatase related 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLPPR3, phospholipid phosphatase related 3
  • Synonyms
    LPPR3, LPR3, PRG-2, PRG2
  • Links
    NCBI Gene ID: 79948
    neXtProt AC: NX_Q6T4P5
    UniProt: Q6T4P5

  • Chr Location
    19p13.3; chr19:812488-823797 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035835 Ensembl Gene Model | MGI Sequence Detail 14160 C57BL/6J ±  kb
transcript ENSMUST00000092325 Ensembl | MGI Sequence Detail 2766 Not Applicable  
polypeptide ENSMUSP00000089979 Ensembl | MGI Sequence Detail 716 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000009905 phospholipid phosphatase-related protein type 3
  • InterPro Domains
    IPR043216 Phosphatidate (PA) phosphatase-related
    IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase
    IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
  • GlyGen
    Q7TPB0 5 sites, 1 O-linked glycan (3 sites)
Molecular
Reagents
less
  • All nucleic 67
    cDNA 67

    Microarray probesets 2
References
more
  • Summaries
    All 39
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:323226 Gross I, et al., Systematic expression analysis of plasticity-related genes in mouse brain development brings PRG4 into play. Dev Dyn. 2022 Apr;251(4):714-728

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory