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Hinfp Gene Detail
Summary
  • Symbol
    Hinfp
  • Name
    histone H4 transcription factor
  • Synonyms
    DKFZp434F162, Mizf
  • Feature Type
    protein coding gene
  • IDs
    MGI:2429620
    NCBI Gene: 102423
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:44203737-44216968 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 24.84 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    399 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2429620
 protein coding gene Chr9:44201509-44217003 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034699
 protein coding gene Chr9:42772093-42784031 (-)
A/J MGP_AJ_G0034680
 protein coding gene Chr9:41587809-41598989 (-)
AKR/J MGP_AKRJ_G0034606
 protein coding gene Chr9:42447191-42457049 (-)
BALB/cJ MGP_BALBcJ_G0034671
 protein coding gene Chr9:41332699-41345052 (-)
C3H/HeJ MGP_C3HHeJ_G0034382
 protein coding gene Chr9:42900056-42913548 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035192
 protein coding gene Chr9:44040874-44054364 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032107
 protein coding gene Chr9:41167912-41177623 (-)
CAST/EiJ MGP_CASTEiJ_G0033704
 protein coding gene Chr9:42740018-42754388 (-)
CBA/J MGP_CBAJ_G0034354
 protein coding gene Chr9:45647557-45661179 (-)
DBA/2J MGP_DBA2J_G0034513
 protein coding gene Chr9:41490499-41500493 (-)
FVB/NJ MGP_FVBNJ_G0034454
 protein coding gene Chr9:40739892-40752471 (-)
LP/J MGP_LPJ_G0034594
 protein coding gene Chr9:43069850-43083140 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034498
 protein coding gene Chr9:47493848-47506483 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035213
 protein coding gene Chr9:42343857-42355200 (-)
PWK/PhJ MGP_PWKPhJ_G0033410
 protein coding gene Chr9:41361828-41372036 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033244
 protein coding gene Chr9:42660631-42670206 (-)
WSB/EiJ MGP_WSBEiJ_G0033817
 protein coding gene Chr9:42382719-42395472 (-)



Homology
more
  • Human Ortholog
    HINFP, histone H4 transcription factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HINFP, histone H4 transcription factor
  • Synonyms
    HiNF-P, MIZF, ZNF743
  • Links
    NCBI Gene ID: 25988
    neXtProt AC: NX_Q9BQA5
    UniProt: Q9BQA5

  • Chr Location
    11q23.3; chr11:119121580-119136059 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit early embryonic lethality associated with delayed hatching and failure of the blastocyst to expand.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    54
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    845
  • Tissues
    73
  • cDNA Data
    49
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032119 Ensembl Gene Model | MGI Sequence Detail 13232 C57BL/6J ±  kb
    transcript ENSMUST00000216508 Ensembl | MGI Sequence Detail 5333 Not Applicable  
    polypeptide ENSMUSP00000149879 Ensembl | MGI Sequence Detail 503 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 52
      cDNA 49
      Primer pair 3

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2142960
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 6
      Gene Ontology 8
      Phenotypes 9
    • Earliest
      J:78123 Kameya S, et al., Mfrp, a gene encoding a frizzled related protein, is mutated in the mouse retinal degeneration 6. Hum Mol Genet. 2002 Aug 1;11(16):1879-86
    • Latest
      J:299723 Kafer GR, et al., A Survey of Essential Genome Stability Genes Reveals That Replication Stress Mitigation Is Critical for Peri-Implantation Embryogenesis. Front Cell Dev Biol. 2020;8:416
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/17/2024
    MGI 6.24     		The Jackson Laboratory