Pgbd1 MGI Mouse Gene Detail - MGI:2441675 - piggyBac transposable element derived 1

Symbol

Pgbd1
Name

piggyBac transposable element derived 1
Synonyms

4921509E05Rik

Feature Type

protein coding gene
IDs

MGI:2441675
NCBI Gene: 319207
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr13:21605445-21625228 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 7.79 cM
Mapping Data

2 experiments

SNPs within 2kb

621 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2441675	protein coding gene	Chr13:21605445-21625255 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0020275	protein coding gene	Chr13:18682858-18705261 (-)
A/J	MGP_AJ_G0020231	protein coding gene	Chr13:18276288-18295933 (-)
AKR/J	MGP_AKRJ_G0020207	protein coding gene	Chr13:18580210-18599901 (-)
BALB/cJ	MGP_BALBcJ_G0020219	protein coding gene	Chr13:18317071-18336748 (-)
C3H/HeJ	MGP_C3HHeJ_G0020020	protein coding gene	Chr13:18672612-18692326 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0020663	protein coding gene	Chr13:19348406-19372846 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018270	protein coding gene	Chr13:16632300-16652584 (-)
CAST/EiJ	MGP_CASTEiJ_G0019557	protein coding gene	Chr13:18479806-18502141 (-)
CBA/J	MGP_CBAJ_G0019984	protein coding gene	Chr13:20015468-20038459 (-)
DBA/2J	MGP_DBA2J_G0020105	protein coding gene	Chr13:17914899-17934904 (-)
FVB/NJ	MGP_FVBNJ_G0020087	protein coding gene	Chr13:17577780-17598198 (-)
LP/J	MGP_LPJ_G0020176	protein coding gene	Chr13:18927081-18950456 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020125	protein coding gene	Chr13:20406860-20428577 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020691	protein coding gene	Chr13:18395654-18417338 (-)
PWK/PhJ	MGP_PWKPhJ_G0019320	protein coding gene	Chr13:17953839-17974002 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0019126	protein coding gene	Chr13:17409229-17430843 (-)
WSB/EiJ	MGP_WSBEiJ_G0019614	protein coding gene	Chr13:18478983-18500428 (-)

Human Ortholog

PGBD1, piggyBac transposable element derived 1

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

PGBD1, piggyBac transposable element derived 1
Synonyms

dJ874C20.4, HUCEP-4, SCAND4
Links

HGNC:19398

NCBI Gene ID: 84547

neXtProt AC: NX_Q96JS3

UniProt: Q96JS3
Chr Location

6p22.1; chr6:28281572-28302549 (+) GRCh38

MGI Vertebrate Homology

Pgbd1 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: PGBD1
Gene Tree

Pgbd1

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Phenotype Summary

14 phenotypes from 1 allele in 1 genetic background
17 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

7
Chemically induced (other)

1
Endonuclease-mediated

1
Gene trapped

1
Radiation induced

1
Targeted

3
Genomic Mutations

2 involving Pgbd1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

27 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

2
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

10

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

54
RefSeq

10
UniProt

4
CCDS

CCDS49209.1, CCDS49210.1

Ensembl

ENSMUSG00000055313 (Evidence)
NCBI Gene

319207

			Length	Strain/Species	Flank
genomic	ENSMUSG00000055313	Ensembl Gene Model \| MGI Sequence Detail	19784	C57BL/6J	± kb
transcript	ENSMUST00000151743	Ensembl \| MGI Sequence Detail	3225	Not Applicable
polypeptide	ENSMUSP00000117669	Ensembl \| MGI Sequence Detail	415	Not Applicable

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UniProt

4 Sequences
InterPro Domains

IPR052638 PiggyBac transposable element-derived

IPR029526 PiggyBac transposable element-derived protein
GlyGen

E9Q492 1 site, 1 N-linked glycan (1 site)

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All nucleic 12

cDNA 12

Microarray probesets 3

Summaries

All 37

Gene Ontology 2

Phenotypes 17
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Pgbd1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr121656	Chr13:21625214-21625239 (-)	1 bp
Tssr121655	Chr13:21624861-21624883 (-)	356 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24