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Ankef1 Gene Detail
Summary
  • Symbol
    Ankef1
  • Name
    ankyrin repeat and EF-hand domain containing 1
  • Synonyms
    Ankrd5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441685
    NCBI Gene: 319196
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:136374241-136397774 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 67.46 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    737 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441685
 protein coding gene Chr2:136343830-136404011 (+)
129S1/SvImJ ENSMUSG00200006770
 protein coding gene Chr2:133400396-133453445 (+)
A/J ENSMUSG00195014927
 protein coding gene Chr2:133449320-133502385 (+)
AKR/J ENSMUSG00220036661
 protein coding gene Chr2:133150089-133203143 (+)
BALB/cJ ENSMUSG00180027054
 protein coding gene Chr2:133265295-133318359 (+)
C3H/HeJ ENSMUSG00175031127
 protein coding gene Chr2:133794944-133848001 (+)
C57BL/6NJ ENSMUSG00215019326
 protein coding gene Chr2:133289770-133342832 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024356
 protein coding gene Chr2:129136524-129198666 (+)
CAST/EiJ ENSTCUG00005010884
 protein coding gene Chr2:132533007-132585217 (+)
CBA/J ENSMUSG00210036514
 protein coding gene Chr2:133695955-133749013 (+)
DBA/2J ENSMUSG00185039383
 protein coding gene Chr2:133330275-133383330 (+)
FVB/NJ ENSMUSG00205025627
 protein coding gene Chr2:132461066-132514129 (+)
JF1/MsJ ENSUMUG00000028843
 protein coding gene Chr2:133106431-133157428 (+)
LP/J ENSMUSG00230008702
 protein coding gene Chr2:135026663-135079720 (+)
NOD/ShiLtJ ENSMUSG00190031248
 protein coding gene Chr2:133390542-133443600 (+)
NZO/HlLtJ ENSMUSG00225001078
 protein coding gene Chr2:143010539-143042454 (+)
PWK/PhJ ENSLUMG00010033407
 protein coding gene Chr2:133137728-133190183 (+)
SPRET/EiJ ENSMSPG00010026069
 protein coding gene Chr2:135525580-135547814 (+)
WSB/EiJ ENSIUOG00005022929
 protein coding gene Chr2:133190294-133243340 (+)



Homology
more
  • Human Ortholog
    ANKEF1, ankyrin repeat and EF-hand domain containing 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANKEF1, ankyrin repeat and EF-hand domain containing 1
  • Synonyms
    ANKRD5
  • Links
    NCBI Gene ID: 63926
    UniProt: Q9NU02

  • Chr Location
    20p12.2; chr20:9986126-10058303 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Ankef1
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    15 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    600
  • Tissues
    3
  • cDNA Data
    10
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319196 NCBI Gene Model | MGI Sequence Detail 23534 C57BL/6J ±  kb
transcript NM_175667 RefSeq | MGI Sequence Detail 2723 Not Specified  
polypeptide Q9D2J7 UniProt | EBI | MGI Sequence Detail 775 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139264
References
more
  • Summaries
    All 50
    Developmental Gene Expression 1
    Diseases 1
    Phenotypes 27
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:386263 Yu S, et al., ANKEF1 is a key axonemal component essential for murine sperm motility and male fertility. Elife. 2025 Dec 29;14
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory