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Tmem87a Gene Detail
Summary
  • Symbol
    Tmem87a
  • Name
    transmembrane protein 87A
  • Synonyms
    A930025J12Rik, Elkin1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441844
    NCBI Gene: 211499
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:120185793-120234594 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 60.31 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1050 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441844
 protein coding gene Chr2:120185790-120234597 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026365
 protein coding gene Chr2:123219859-123270949 (-)
A/J MGP_AJ_G0026326
 protein coding gene Chr2:118169277-118217772 (-)
AKR/J MGP_AKRJ_G0026305
 protein coding gene Chr2:121470290-121519421 (-)
BALB/cJ MGP_BALBcJ_G0026339
 protein coding gene Chr2:118412891-118461720 (-)
C3H/HeJ MGP_C3HHeJ_G0026085
 protein coding gene Chr2:121942629-121993639 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026786
 protein coding gene Chr2:127232952-127282648 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024166
 protein coding gene Chr2:113191196-113239181 (-)
CAST/EiJ MGP_CASTEiJ_G0025547
 protein coding gene Chr2:122256394-122305682 (-)
CBA/J MGP_CBAJ_G0026061
 protein coding gene Chr2:131687809-131737687 (-)
DBA/2J MGP_DBA2J_G0026200
 protein coding gene Chr2:117559461-117607970 (-)
FVB/NJ MGP_FVBNJ_G0026162
 protein coding gene Chr2:116395676-116443853 (-)
LP/J MGP_LPJ_G0026301
 protein coding gene Chr2:123478896-123526717 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026181
 protein coding gene Chr2:135999152-136050632 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026841
 protein coding gene Chr2:121593510-121644906 (-)
PWK/PhJ MGP_PWKPhJ_G0025283
 protein coding gene Chr2:117161054-117210381 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025082
 protein coding gene Chr2:120781917-120841221 (-)
WSB/EiJ MGP_WSBEiJ_G0025616
 protein coding gene Chr2:122430234-122479032 (-)



Homology
more
  • Human Ortholog
    TMEM87A, transmembrane protein 87A
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM87A, transmembrane protein 87A
  • Synonyms
    ELKIN1
  • Links
    NCBI Gene ID: 25963
    neXtProt AC: NX_Q8NBN3
    UniProt: Q8NBN3

  • Chr Location
    15q15.1; chr15:42210447-42273584 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display loss of touch sensitivity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    8
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033808 Ensembl Gene Model | MGI Sequence Detail 48802 C57BL/6J ±  kb
transcript ENSMUST00000090046 Ensembl | MGI Sequence Detail 2897 Not Applicable  
polypeptide ENSMUSP00000087500 Ensembl | MGI Sequence Detail 560 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345910 Chakrabarti S, et al., Touch sensation requires the mechanically gated ion channel ELKIN1. Science. 2024 Mar;383(6686):992-998
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory