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Sf3b2 Gene Detail
Summary
  • Symbol
    Sf3b2
  • Name
    splicing factor 3b, subunit 2
  • Synonyms
    145kDa, 2610311M13Rik, 2810441F20Rik, B230398H18Rik, SAP145, SF3b1, SF3b145, SF3b150
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441856
    NCBI Gene: 319322
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5323960-5345483 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 4.29 cM, cytoband A
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    453 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441856
 protein coding gene Chr19:5323949-5345485 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024696
 protein coding gene Chr19:2225312-2246614 (-)
A/J MGP_AJ_G0024662
 protein coding gene Chr19:2102161-2125136 (-)
AKR/J MGP_AKRJ_G0024635
 protein coding gene Chr19:2166586-2191086 (-)
BALB/cJ MGP_BALBcJ_G0024662
 protein coding gene Chr19:2102669-2126385 (-)
C3H/HeJ MGP_C3HHeJ_G0024430
 protein coding gene Chr19:2170402-2192632 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025109
 protein coding gene Chr19:2279327-2306384 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022539
 protein coding gene Chr19:2014270-2035196 (-)
CAST/EiJ MGP_CASTEiJ_G0023902
 protein coding gene Chr19:2193041-2216871 (-)
CBA/J MGP_CBAJ_G0024402
 protein coding gene Chr19:2376012-2399661 (-)
DBA/2J MGP_DBA2J_G0024529
 protein coding gene Chr19:2085524-2107092 (-)
FVB/NJ MGP_FVBNJ_G0024496
 protein coding gene Chr19:2089846-2114010 (-)
LP/J MGP_LPJ_G0024615
 protein coding gene Chr19:2203899-2226993 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024526
 protein coding gene Chr19:2235486-2260630 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025157
 protein coding gene Chr19:2166739-2191876 (-)
PWK/PhJ MGP_PWKPhJ_G0023648
 protein coding gene Chr19:2123795-2146690 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023453
 protein coding gene Chr19:2155407-2180126 (-)
WSB/EiJ MGP_WSBEiJ_G0023964
 protein coding gene Chr19:2180064-2202583 (-)



Homology
more
  • Human Ortholog
    SF3B2, splicing factor 3b subunit 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SF3B2, splicing factor 3b subunit 2
  • Synonyms
    CFM, Cus1, HFM, SAP145, SF3b1, SF3B145, SF3b150
  • Links
    NCBI Gene ID: 10992
    neXtProt AC: NX_Q13435
    UniProt: Q13435

  • Chr Location
    11q13.1; chr11:66050729-66069308 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SF3B2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    8
  • cDNA Data
    25
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024853 Ensembl Gene Model | MGI Sequence Detail 21524 C57BL/6J ±  kb
transcript ENSMUST00000025774 Ensembl | MGI Sequence Detail 3222 Not Applicable  
polypeptide ENSMUSP00000025774 Ensembl | MGI Sequence Detail 878 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 25
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1914417, MGI:1925755
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory