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Defb20 Gene Detail
Summary
  • Symbol
    Defb20
  • Name
    defensin beta 20
  • Synonyms
    9230107O10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442320
    NCBI Gene: 319579
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:152318983-152321645 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 75.11 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    171 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442320
 protein coding gene Chr2:152318983-152321854 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026662
 protein coding gene Chr2:157038792-157041661 (+)
A/J MGP_AJ_G0026628
 protein coding gene Chr2:150763182-150766052 (+)
AKR/J MGP_AKRJ_G0026598
 protein coding gene Chr2:155170946-155173817 (+)
BALB/cJ MGP_BALBcJ_G0026637
 protein coding gene Chr2:151073963-151076834 (+)
C3H/HeJ MGP_C3HHeJ_G0026380
 protein coding gene Chr2:155549755-155552626 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027086
 protein coding gene Chr2:161607862-161610733 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024457
 protein coding gene Chr2:144354295-144357387 (+)
CAST/EiJ MGP_CASTEiJ_G0025841
 protein coding gene Chr2:155788826-155791788 (+)
CBA/J MGP_CBAJ_G0026358
 protein coding gene Chr2:167526839-167529709 (+)
DBA/2J MGP_DBA2J_G0026494
 protein coding gene Chr2:149980677-149983548 (+)
FVB/NJ MGP_FVBNJ_G0026460
 protein coding gene Chr2:148432776-148435554 (+)
LP/J MGP_LPJ_G0026598
 protein coding gene Chr2:157183964-157186833 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026481
 protein coding gene Chr2:171626849-171629721 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027142
 protein coding gene Chr2:155049467-155052338 (+)
PWK/PhJ MGP_PWKPhJ_G0025575
 protein coding gene Chr2:149498014-149500879 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025378
 protein coding gene Chr2:153881204-153884140 (+)
WSB/EiJ MGP_WSBEiJ_G0025911
 protein coding gene Chr2:155969528-155972395 (+)



Homology
more
  • Human Ortholog
    DEFB128, defensin beta 128
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DEFB128, defensin beta 128
  • Synonyms
    DEFB-28, DEFB28, hBD-28
  • Links
    NCBI Gene ID: 245939
    neXtProt AC: NX_Q7Z7B8
    UniProt: Q7Z7B8

  • Chr Location
    20p13; chr20:187853-189711 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    3
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 319579 NCBI Gene Model | MGI Sequence Detail 2663 C57BL/6J ±  kb
    transcript NM_176950 RefSeq | MGI Sequence Detail 481 C57BL/6  
    polypeptide Q30KP3 UniProt | EBI | MGI Sequence Detail 96 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 3
      cDNA 3

      Microarray probesets 2
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 11
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory