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Fam168a Gene Detail
Summary
  • Symbol
    Fam168a
  • Name
    family with sequence similarity 168, member A
  • Synonyms
    2610030B18Rik, B930006L02Rik, mKIAA0280
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442372
    NCBI Gene: 319604
  • Alliance
    gene page
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:100355842-100490863 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 54.39 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3484 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442372
 protein coding gene Chr7:100355594-100490863 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032576
 protein coding gene Chr7:103683314-103756461 (+)
A/J MGP_AJ_G0032550
 protein coding gene Chr7:101048560-101129586 (+)
AKR/J MGP_AKRJ_G0032486
 protein coding gene Chr7:103466978-103536759 (+)
BALB/cJ MGP_BALBcJ_G0032561
 protein coding gene Chr7:100731987-100817056 (+)
C3H/HeJ MGP_C3HHeJ_G0032276
 protein coding gene Chr7:103867380-103924351 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033059
 protein coding gene Chr7:107616463-107684155 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030053
 protein coding gene Chr7:103390322-103522594 (+)
CAST/EiJ MGP_CASTEiJ_G0031603
 protein coding gene Chr7:95347812-95481445 (+)
CBA/J MGP_CBAJ_G0032243
 protein coding gene Chr7:111331949-111399093 (+)
DBA/2J MGP_DBA2J_G0032394
 protein coding gene Chr7:99399481-99457394 (+)
FVB/NJ MGP_FVBNJ_G0032351
 protein coding gene Chr7:99107320-99247769 (+)
LP/J MGP_LPJ_G0032484
 protein coding gene Chr7:104951674-105095005 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032384
 protein coding gene Chr7:112717402-112776523 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033081
 protein coding gene Chr7:102742660-102797981 (+)
PWK/PhJ MGP_PWKPhJ_G0031321
 protein coding gene Chr7:92523259-92579152 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031164
 protein coding gene Chr7:90056638-90115058 (+)
WSB/EiJ MGP_WSBEiJ_G0031720
 protein coding gene Chr7:103440361-103504263 (+)



Homology
more
  • Human Ortholog
    FAM168A, family with sequence similarity 168 member A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM168A, family with sequence similarity 168 member A
  • Synonyms
    KIAA0280, TCRP1
  • Links
    NCBI Gene ID: 23201
    neXtProt AC: NX_Q92567
    UniProt: Q92567

  • Chr Location
    11q13.4; chr11:73400487-73598189 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    19
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000029461 Ensembl Gene Model | MGI Sequence Detail 135022 C57BL/6J ±  kb
    transcript ENSMUST00000208013 Ensembl | MGI Sequence Detail 1129 Not Applicable  
    polypeptide ENSMUSP00000146839 Ensembl | MGI Sequence Detail 260 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 19

      Microarray probesets 10
    Other
    Accession IDs
    less
    MGI:1916473
    References
    more
    • Summaries
      All 48
      Gene Ontology 3
      Phenotypes 21
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory