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Nfrkb Gene Detail
Summary
  • Symbol
    Nfrkb
  • Name
    nuclear factor related to kappa B binding protein
  • Synonyms
    A530090G11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442410
    NCBI Gene: 235134
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:31297488-31332629 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 16.86 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    843 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442410
 protein coding gene Chr9:31297476-31332629 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034519
 protein coding gene Chr9:29071306-29111923 (+)
A/J MGP_AJ_G0034497
 protein coding gene Chr9:28356540-28391064 (+)
AKR/J MGP_AKRJ_G0034423
 protein coding gene Chr9:28930521-28966210 (+)
BALB/cJ MGP_BALBcJ_G0034488
 protein coding gene Chr9:28221156-28257240 (+)
C3H/HeJ MGP_C3HHeJ_G0034200
 protein coding gene Chr9:29290411-29330172 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035009
 protein coding gene Chr9:30070001-30107875 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031939
 protein coding gene Chr9:27179780-27215221 (+)
CAST/EiJ MGP_CASTEiJ_G0033523
 protein coding gene Chr9:29153151-29188509 (+)
CBA/J MGP_CBAJ_G0034174
 protein coding gene Chr9:31055564-31092064 (+)
DBA/2J MGP_DBA2J_G0034331
 protein coding gene Chr9:28362897-28397996 (+)
FVB/NJ MGP_FVBNJ_G0034274
 protein coding gene Chr9:27765548-27801143 (+)
LP/J MGP_LPJ_G0034417
 protein coding gene Chr9:29284852-29324054 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034318
 protein coding gene Chr9:32693695-32732085 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035029
 protein coding gene Chr9:28933294-28969936 (+)
PWK/PhJ MGP_PWKPhJ_G0033228
 protein coding gene Chr9:28299552-28337049 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033062
 protein coding gene Chr9:29035632-29074582 (+)
WSB/EiJ MGP_WSBEiJ_G0033638
 protein coding gene Chr9:28682129-28717869 (+)



Homology
more
  • Human Ortholog
    NFRKB, nuclear factor related to kappaB binding protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NFRKB, nuclear factor related to kappaB binding protein
  • Synonyms
    INO80G
  • Links
    NCBI Gene ID: 4798
    neXtProt AC: NX_Q6P4R8
    UniProt: Q6P4R8

  • Chr Location
    11q24.3; chr11:129863636-129895590 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    878
  • Tissues
    105
  • cDNA Data
    101
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042185 Ensembl Gene Model | MGI Sequence Detail 35142 C57BL/6J ±  kb
transcript ENSMUST00000086167 Ensembl | MGI Sequence Detail 5161 Not Applicable  
polypeptide ENSMUSP00000083341 Ensembl | MGI Sequence Detail 1296 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000011183 nuclear factor related to kappa-B-binding protein
    (term hierarchy)
  • InterPro Domains
    IPR044867 DEUBAD domain
    IPR025220 NFRKB winged helix-like domain
    IPR038106 NFRKB winged helix-like domain superfamily
    IPR024867 Nuclear factor related to kappa-B-binding protein
  • GlyGen
    Q6PIJ4 27 sites, 1 O-linked glycan (27 sites)
Molecular
Reagents
less
  • All nucleic 102
    cDNA 101
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:221224 Min JN, et al., The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability. Cell Res. 2013 Dec;23(12):1396-413
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory