Sertm2 Gene Detail

Summary

• Symbol
  Sertm2
• Name
  serine rich and transmembrane domain containing 2
• Synonyms
  A730046J19Rik

• Feature Type
  protein coding gene
• IDs
  MGI:2442684
  NCBI Gene: 319764
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  ChrX:142936691-142949270 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome X, 65.23 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  340 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2442684	protein coding gene	ChrX:142936691-142949270 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0007567	lincRNA gene	ChrX:141704736-141717319 (+)
A/J	MGP_AJ_G0007566	lincRNA gene	ChrX:141015831-141029430 (+)
AKR/J	MGP_AKRJ_G0007536	lincRNA gene	ChrX:145595074-145607645 (+)
BALB/cJ	MGP_BALBcJ_G0007540	lincRNA gene	ChrX:139270878-139283460 (+)
C3H/HeJ	MGP_C3HHeJ_G0007487	lincRNA gene	ChrX:141788398-141800975 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0007713	lincRNA gene	ChrX:145708349-145720916 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0006889	lincRNA gene	ChrX:132612753-132626121 (+)
CAST/EiJ	MGP_CASTEiJ_G0007389	lincRNA gene	ChrX:122449162-122461844 (+)
CBA/J	MGP_CBAJ_G0007468	lincRNA gene	ChrX:150211092-150223669 (+)
DBA/2J	MGP_DBA2J_G0007493	lincRNA gene	ChrX:140117947-140130522 (+)
FVB/NJ	MGP_FVBNJ_G0007509	lincRNA gene	ChrX:139325044-139337603 (+)
LP/J	MGP_LPJ_G0007573	lincRNA gene	ChrX:142635503-142648087 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0007488	lincRNA gene	ChrX:157961062-157973834 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0007716	lincRNA gene	ChrX:140982576-140995162 (+)
PWK/PhJ	MGP_PWKPhJ_G0007326	lincRNA gene	ChrX:119253971-119266662 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0007230	lincRNA gene	ChrX:122987825-123000403 (+)
WSB/EiJ	MGP_WSBEiJ_G0007450	lincRNA gene	ChrX:139357672-139370251 (+)

Homology

• Human Ortholog
  SERTM2, serine rich and transmembrane domain containing 2

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  SERTM2, serine rich and transmembrane domain containing 2
  
• Synonyms
  CARDEL, DKFZp686D0853, LINC00890
• Links
  HGNC:48576

  NCBI Gene ID: 401613

  UniProt: A0A1B0GWG4

  
  
• Chr Location
  Xq23; chrX:111511645-111522399 (+)  GRCh38

---

• MGI Vertebrate Homology
  Sertm2 stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: SERTM2
• Gene Tree
  Sertm2
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  1 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  2

Expression

• Assay Results
  706
• cDNA Data
  4
• Literature Summary
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  29
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS90758.1

• Ensembl
  ENSMUSG00000085139 (Evidence)
• NCBI Gene
  319764

Representative Sequences			Length	Strain/Species
genomic	319764	NCBI Gene Model | MGI Sequence Detail	12580	C57BL/6J
transcript	NM_001354493	RefSeq | MGI Sequence Detail	4724	C57BL/6
polypeptide	A0A1B0GSN8	UniProt | EBI | MGI Sequence Detail	89	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000059670 serine-rich and transmembrane domain-containing 2
  (term hierarchy)
• InterPro Domains
  IPR031741 Serine-rich and transmembrane domain-containing protein
• GlyGen
  A0A1B0GSN8 1 site

Molecular
Reagents

• All nucleic 4

  cDNA 4

Other
Accession IDs

MGI:7414208

References

• Summaries
  All 13

  Developmental Gene Expression 1

  Gene Ontology 2

  Phenotypes 1
• Earliest
  J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
• Latest
  J:348859 Lee Y, et al., Transcriptional control of motor pool formation and motor circuit connectivity by the LIM-HD protein Isl2. Elife. 2023 Oct 23;12

TSS for Sertm2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr162272	ChrX:142936692-142936710 (+)	10 bp
Tssr162273	ChrX:142936712-142936761 (+)	46 bp